When it comes to choosing the best fertility pills and supplements to help you get pregnant, the options can be overwhelming. You might be unsure which ingredients are effective or how to navigate the various claims made by different companies. Your search may be filled with uncertainty, leaving you to wonder which option will actually support your efforts in conception.
While there are fertility supplements on the market that claim to enhance reproductive health, the research backing their efficacy is mixed. Some studies support the effectiveness of specific ingredients, such as folic acid and myo-inositol, while other supplements lack robust clinical evidence. Our team considered both the available research and the gaps in scientific support, evaluating each product based on price, ingredients, purity, effectiveness, side effects, and customer feedback to help you make an informed choice.
Medical disclaimer: This article is intended for educational and informational purposes only. It is not intended as a substitute for medical advice. For health advice, contact a licensed healthcare provider. These products should not be used as a guarantee of successful contraception.
Editor’s choice
Ritual’s Fertility Support tops our list as a 3-in-1 vegan powder supplement designed to support conception outcomes by promoting follicular, ovarian, and egg health. Developed with OB/GYNs and fertility specialists, it includes clinically-studied ingredients like Myo-Inositol, NAC, and CoQ10 to help regulate ovulation, balance hormone levels, and provide antioxidant support.
Our picks for the best fertility pills and supplements to get pregnant
- Best powder: Ritual Fertility Support
- Best Omega-3 supplement: Transparent Labs Krill Oil
- Best folic acid supplement: Nature Made Folic Acid
- Best vitamin D supplement: Thorne Vitamin D Liquid
- Best CoQ10 supplement: Garden of Life Raw CoQ10
Compare best fertility pills and supplements to get pregnant
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| Ritual Fertility Support | Transparent Labs Krill Oil | Nature Made Folic Acid | Thorne Vitamin D Liquid | Garden of Life Raw CoQ10 | |
| Rating | |||||
| Price | $99 | $34.99 | $6.31 | $17.00 | $38.99 |
| Active ingredients | CoQ10, NAC (N-Acetylcysteine), Myo-inositol | EHA, DHA, choline, astaxanthin | Folic acid | Vitamin D3 | Raw CoQ10, raw cold-pressed chia seed oil omega-3s, omega- 6s, omega-9s |
| WarrantyForm | Vegan powder | Liquid softgel | Tablet | Liquid | Capsule |
| Dose | One scoop, twice a day | Two liquid softgels | One tablet | Two drops | One capsule |
Best powder supplement to get pregnant: Ritual Fertility Support
Key product features
What you should know
Ritual Fertility Support is a preconception supplement designed for those planning to conceive. This powder blend includes CoQ10, Myo-inositol, and NAC, ingredients clinically studied to support ovarian and egg health.
- Each serving provides targeted nutrients to aid reproductive health, with a cost of $99 that may be higher than some alternatives.
- This product is particularly well-suited for women aiming to optimize their fertility.
- Users should note that it comes as a powder and needs to be mixed into water, which may not appeal to everyone.
- Users have to drink it twice a day, which if you don’t like the lemon flavor, might be very inconvenient.
Why we like Ritual Fertility Support as best powder
Ritual Fertility Support powder earns its top spot due to its combination of high-quality, research-backed ingredients that support overall fertility health. This supplement is designed specifically for those planning to conceive, offering a blend of CoQ10, NAC, and Myo-inositol—each known for their role in promoting ovarian and egg health.
CoQ10, for example, is a powerful antioxidant that supports cellular energy and egg quality (1), while Myo-inositol is a key player in regulating ovarian function and improving insulin sensitivity (2), which can be beneficial for those with conditions like PCOS. NAC (N-Acetyl Cysteine) further contributes by promoting detoxification and improving reproductive health markers. (3)
What sets Ritual apart is their dedication to ingredient traceability and ethical sourcing. All ingredients are non-GMO, gluten-free, and allergen-free, making this powder suitable for a wide variety of users. Additionally, Ritual ensures transparency in its formulations, showing exactly where their ingredients come from and the science behind each one. This level of commitment is echoed by their reliance on clinical research and collaboration with experts to continually refine their products.
To use the product, you start with 8-12 oz of any liquid and add one scoop of the powder in. Mix the powder in the liquid with a spoon, frother, or shaker. The supplement should be taken twice a day, once in the morning and once at night.
The lemon-flavored powder format offers a unique alternative to capsules, catering to those who prefer a supplement that can be mixed into water or other beverages. It can also be a great option for individuals who have difficulty swallowing pills. However, this convenience comes with a higher price per serving of $1.65 compared to many traditional capsule supplements, but the quality and ethical practices behind the product help justify the cost.
The subscription model ensures that users consistently receive their product each month, making it easier to stick to a preconception routine. This automated delivery system is especially useful for busy individuals, as it eliminates the need to manually reorder. You can also pause or cancel the subscription at any time, with no hidden fees and a 30-day money-back guarantee if you aren’t satisfied with the product.
Overall, Ritual Fertility Support is an excellent choice for individuals looking for a science-backed, ethically sourced fertility supplement in a convenient powder format. Though it may be a little pricier than other options, its quality, transparency, and ease of use make it a standout in the preconception supplement space.
What our experts say
“Any organization that promotes transparency in its product formulation gets a thumbs up by me,” according to Dr. Aneesha Dhargalkar, MD. “It is important to know the ingredient make up of any supplement that you are taking, and Ritual ensures that you do. In addition, the ingredients within this product all work synergistically to promote fertility health. This means that the combination of these ingredients improves fertility greater than each individual ingredient. Each of the ingredients in Ritual has been proven to increase ovulation and improve fertility health in women with specific medical conditions. For example, CoQ10 was found to increase pregnancy rates in women using assisted reproductive technology techniques. (4) And, for women with PCOS, studies have shown that myo-inositol help restore ovulation and improve egg quality and embryo development. (5) Ritual Fertility Support is a good supplement option for anyone looking to improve their fertility health, However, it is always important to make sure to consult with your medical provider before trying any fertility supplements.”
Specs
| Form | Powder |
| Daily dose | One scoop twice a day |
| Third-party tested | Yes |
| Number of servings | 60 |
| Price per serving | $1.65 |
Best Omega-3 supplement to get pregnant: Transparent Labs Krill Oil
Key product features
What you should know
Transparent Labs Krill Oil offers a reliable source of omega-3 fatty acids for women looking to become pregnant. It contains eicosatetraenoic acid (EPA) and docosahexaenoic acid (DHA) to help support fertility and fetal development. (8)
- This omega-3 supplement contains Superba ™ krill oil, which is easier to digest and more bioavailable than other fish oil supplements.
- Each serving costs $1.17, which is almost double the price of similar krill oil supplements.
- This product is best for women planning to become pregnant and those who are already pregnant.
- This supplement contains choline, which is beneficial for fertility and fetal development. (9)
Why we like Transparent Labs Krill Oil as best Omega-3 supplement
Transparent Labs Krill Oil is the top pick for the best Omega-3 supplement because it provides a sustainable-sourced, highly bioavailable form of omega-3 fatty acids. This krill oil supplement is made with Superba 2 ™, a well-researched form of krill oil linked to numerous health benefits. (25)
In addition to health benefits such as improving cardiovascular health and cognition, omega-3 fatty acids play an important role in fertility and fetal development. (10)
Studies have shown that omega-3 deficiency increases the risk of miscarriage. Alternatively, a diet high in omega-3 fatty acids can improve fertility by “improving hormonal balance, oocyte quality, embryo implantation, [and] menstrual cycle function.” (8)
What is impressive about Transparent Labs Krill Oil is its phospholipid form of omega-3. This form is more easily absorbed by the body than other fish oil supplements. This ensures the EPA and DHA fatty acids are delivered to the reproductive organs to support conception and pregnancy.
Transparent Labs Krill Oil not only provides sufficient omega-3s, but it also contains astaxanthin and choline.
- Astaxanthin is a powerful antioxidant that helps protect reproductive cells from oxidative stress, which may be damaging to fertility. (11) Additionally, it helps stabilize krill oil, reducing the risk of spoilage.
- Choline is an essential nutrient that supports fertility and reproductive health. Adequate choline can improve egg quality and embryo development and is vital for neural tube formation and fetal brain development. (12)
The price point for Transparent Labs Krill Oil is pricier than other fish oil supplements, but you can subscribe and save. If you subscribe, you save $4 and receive free shipping. There’s also a no-commitment option if you want to try out one bottle to see how you like it. You can also checkout as a guest, so creating an account is unnecessary.
The serving size for this supplement is two liquid soft gels daily, but you can take up to four capsules daily. Ideally, you should take each dose several hours apart. You can take them at any time during the day, but it’s best to take them with a meal. The good news is these supplements do not have a fishy aftertaste or cause fish burps, so you don’t have to worry about this supplement ruining the taste of your food.
Please note this supplement is not suitable for individuals with a shellfish allergy. Additionally, if you are taking anticoagulants (blood thinners) or have a blood clotting disorder, talk with your healthcare provider before taking them.
What our experts say
“Omega-3 fatty acids are an important supplement during both the conception and prenatal periods,” said Dr. Dhargalkar. “Regarding conception, the antioxidant properties of omega-3 fatty acids can help protect a woman’s egg from oxidative damage, thereby increasing the likelihood of a healthy egg and embryo. In the prenatal period, omega-3 fatty acids, specifically EPA and DHA (which are found in Transparent Labs Krill Oil), are necessary for fetal brain development and optimal cognition. They also have anti-inflammatory effects which have been shown to reduce pre-term birth.”
“Omega-3 is an essential fatty acid not just in pregnancy but in general day-to-day,” adds Dr. Dawoodbhoy. “Omega-3 can benefit pregnancy by aiding in brain and eye development as well as reducing the risk of postpartum depression. It is great that there is no fishy aftertaste, as pregnancy increases gastric reflux and the chances of tasting this. There has been some research showing the benefit of taking Omega-3 to improve fertility as it can improve hormone regulation, embryo implantation, and sperm quality.”
Specs
| Form | Liquid soft gel |
| Daily dose | 2-4 capsules |
| Third-party tested | Yes |
| Number of servings | 30 |
| Price per serving | $1.17 |
Best folic acid supplement to get pregnant: Nature Made Folic Acid
Key product features
What you should know
Nature Made Folic Acid contains 400 mcg of folic acid, which is the recommended amount of folic acid for women of childbearing age. Folic acid is crucial for reducing the risk of fetal neural tube defects. (13)
- This folic acid supplement includes 400 mcg of folic acid, the recommended amount for women looking to become pregnant.
- Each serving costs $0.03, which is less expensive than other name-brand folic acid supplements.
- This product is specifically designed for women of childbearing age, ranging from age 16 to 49.
- This supplement contains 70 mg of calcium. Calcium supplementation has been shown to prevent pre-eclampsia (high blood pressure in pregnancy) and preterm birth. (14)
Why we like Nature Made Folic Acid as best folic acid supplement
Nature Made Folic Acid is an inexpensive and effective supplement that promotes reproductive health. Folic acid, a synthetic form of folate (vitamin B9), is essential for all women of reproductive age. It helps prevent fetal neural tube defects, which occur when the neural tube does not close properly. The most common neural tube defects include spina bifida, anencephaly, and encephalocele. (7) These conditions affect the baby’s brain and spine.
The importance of folic acid in the preconception period cannot be understated, and that’s why we were pleased to find Nature Made Folic Acid as the best option. It’s recommended to start taking a supplement that contains 400–800 mcg of folate or folic acid at least one month before conception and continue through the first 12 weeks of pregnancy. (24) The neural tube closes at 12 weeks, but it’s still best to continue to take folic acid throughout your entire pregnancy.
Firstly, we appreciate Nature Made’s commitment to quality and purity. This folic acid supplement is USP-verified, which means it satisfies potency, purity, and consistency criteria. This certification ensures that each dose contains exactly 400 mcg of folic acid.
This budget-friendly supplement costs only $0.03 for each serving. Additionally, Nature Made is easy to purchase online or in-store. It is available at retailers such as Wal-Mart, CVS, and Walgreens. Plus, you won’t have to repurchase very often. Each bottle contains 250 pills, which is a 250-day supply.
It’s worth noting that while this supplement is easy to obtain, it may not be as easy to take. Many customers complained that the pill had a grainy texture and that it often started to dissolve in the mouth before swallowing, which can cause an unpleasant taste and sensation in the mouth. However, one plus side is the pills are relatively small. They are about one inch long, so these should be small enough to take even if you struggle swallowing pills.
Additionally, this supplement could cause nausea if taken on an empty stomach. To prevent this, you should take the supplement with a meal or snack.
What our experts say
“Nature Made Folic Acid contains the recommended amount of folic acid for women who are both trying to get pregnant and are, in fact, pregnant,” said Dr. Dhargalkar. “We have already discussed the benefits of taking folic acid during pregnancy. This vitamin also contains 70 mg of calcium, a supplement essential for fetal skeletal development. Calcium may also reduce the risk of developing a hypertensive disorder in pregnancy, such as preeclampsia. This is most helpful for those pregnant patients with a low baseline dietary calcium intake.”
“Folic acid is one of the most crucial vitamins in preconception and pregnancy,” adds Dr. Dawoodboy. “Its primary role is to prevent neural tube defects by aiding in brain and spine development. 400mcg daily is sufficient. However, if there is a higher chance of neural tube defects in your pregnancy, you should take a higher dose of 5mg.”
What customers are saying
Amazon customers appreciate the price point and efficacy of this product. It’s a popular choice with over 23,000 reviews and a 4.8 out of 5-star rating.
Verified Amazon buyer Destiny recalls, “I read so many reviews stating how important folic acid is when trying to conceive. I was initially taking the folic acid before I began taking prenatal vitamins.” She describes this supplement as a “good buy” and “quite easy to swallow”.
“I did purchase this because I am pregnant and need the discount for my long list of vitamins. The 3-pack pricing is really good. However, the tablet melts far too quickly. I wish a coating would be added to the pill.”
Georgia, Verified Amazon buyer
Another verified Amazon buyer, Morgan, reports using this folic acid supplement during conception and pregnancy. Her feedback is short and simple: “It’s good.”
Specs
| Form | Tablet |
| Daily dose | One tablet |
| Third-party tested | Yes |
| Number of servings | 250 |
| Price per serving | $0.03 |
Best vitamin D supplement to get pregnant: Thorne Vitamin D Liquid
Key product features
What you should know
Thorne Vitamin D Liquid is an easy-to-take vitamin D supplement that supports fertility. Studies have shown that women with higher vitamin D levels are more likely to conceive and less likely to experience pregnancy loss. (17)
- This vitamin D supplement contains 1,100 IU per unflavored liquid serving.
- Thorne is a budget-friendly option, coming in at $0.03 per serving.
- This product is great for women during preconception and pregnancy.
- This supplement is free of lactose, unlike many other vitamin D supplements.
- You can personalize your dosage by increasing or decreasing the amount of dispensed drops.
Why we like Thorne Vitamin D Liquid as best vitamin D supplement
Thorne’s Vitamin D supplement is a great budget-friendly option that impressed us with its high-quality formula and commitment to purity and bioavailability.
Vitamin D plays an important part in reproductive health. Deficiencies have been linked to pregnancy loss and increased risk of pregnancy complications. (17) Increasing vitamin D levels may help prevent such complications.
One of the standout features of Thorne’s vitamin D supplement is its use of the D3 form of vitamin D, which is more effective than D2, which is often found in other supplements. Your body can better absorb and use D3, and you will reap its full benefits.
Something else that stood out to us is that Thorne runs four rounds of testing for each product. It tests its raw materials, in-process batches, and finished products for purity. This compares to other competitors that only do one or two rounds of testing.
Thorne’s recipe is free of lactose, allergies, and chemical ingredients, making it even more impressive. Furthermore, this supplement is an unflavored liquid, so it can be easier to take if you have problems swallowing pills. You can drop it under your tongue or mix it into a food or beverage. Customers report mixing it into coffee, milk, tea, yogurt, and smoothies. The recommended dose is two drops, which provides 1,000 IU or 25 mcg of vitamin D.
However, the packaging still needs improvement. Although the dropper allows for personalized dosing, many customers report difficulties getting the liquid out of the dropper at all. If you find yourself having a difficult time with the dropper, this is what Thorne recommends to do:
- Remove the bottle cap.
- Hold the bottle down at a 45-degree angle.
- Wait for the drops. (Don’t shake the bottle)
It’s easy to argue the supplement’s strengths may outweigh the finicky dropper. At $0.03 per serving, Thorne’s Vitamin D is a cost-effective option without compromising quality.
You can buy one bottle of this vitamin D, which should last a while. But if you like to plan, you can always subscribe and save with Amazon Prime to receive a discount and your orders at your preferred frequency.
What our experts say
“As mentioned before, vitamin D is an essential supplement during conception,” said Dr. Dhargalkar. “In the prenatal period, vitamin D supplementation may reduce the risk of various adverse pregnancy outcomes, including preeclampsia and gestational diabetes. Thorne Vitamin D Liquid specifically contains vitamin D3, which has been found to raise vitamin D levels higher and longer than vitamin D2. Many pregnant women experience difficulty swallowing pills, so the liquid formulation of this supplement is an added advantage to an already great product.”
“We produce Vitamin D naturally with adequate sun exposure; however, countries with minimal sunlight during winter can have low levels of Vitamin D and require supplementation. There has been evidence that low Vitamin D levels are a risk factor for low fertility. This level of Vitamin D is adequate in maintaining a healthy level in the blood and can, in turn, boost fertility,” states Dr. Dawoodbhoy.
What customers are saying
Many Amazon customers were pleased with how easy this supplement is to take. You can administer it under your tongue or mix it into a drink or food.
“Sometimes I just get tired of taking pills and these drops are a great alternative. They mix into anything and don’t add any flavor!”
Jane, Amazon
Other customers report the efficacy of this vitamin D supplement, sharing that their lab values increased after use. Verified Amazon buyer Lila A. says, “Blood tests were good—I’m happy with the product!”
However, many customers were disappointed they couldn’t dispense the liquid. Verified Amazon buyer K. Mitchell writes, “I can’t speak to the product itself because I can’t get the vitamin D out! As others have mentioned, the dispenser doesn’t dispense!”
Specs
| Form | Liquid |
| Daily dose | Two drops |
| Third-party tested | Yes |
| Number of servings | 600 |
| Price per serving | $0.03 |
Best CoQ10 supplement to get pregnant: Garden of Life Raw CoQ10
Key product features
What you should know
Garden of Life Raw CoQ10 provides 200 mg of CoQ10 without artificial ingredients. CoQ10 is a powerful antioxidant that reduces oxidative stress and helps produce energy in your cells.
- This supplement includes 200 mg of CoQ10, a raw probiotic blend, and a raw fruit and vegetable blend.
- Garden of Life CoQ10 costs $0.65, which is more expensive than other CoQ10 supplements.
- This product is best for the preconception period. Studies on CoQ10 during pregnancy are limited.
- The probiotic blend may cause gastrointestinal upset such as gas, bloating, stomach upset, or diarrhea. These symptoms usually resolve within a few days.
- These capsules are unflavored and vegan-friendly.
Why we like Garden of Life Raw CoQ10 as best CoQ10 supplement
With its powerful 200 mg of CoQ10, Garden of Life Raw CoQ10 stands out as a comprehensive supplement meant to promote general health and fertility.
CoQ10 is necessary for the production of energy in your cells and is a powerful antioxidant that reduces oxidative stress in your body. (26) Oxidative stress occurs when harmful molecules called free radicals build up and damage your cells; antioxidants help neutralize these damaging molecules.
CoQ10’s powerful antioxidant properties are particularly important for women because egg quality declines with age due to the build-up of free radicals. CoQ10 helps maintain the health and viability of your eggs by reducing oxidative stress. (23) Studies have even shown women undergoing in vitro fertilization had increased chances of conception while taking CoQ10. (23)
In addition to Co110, Garden of life added a raw fruit and vegetable blend and a raw probiotic blend in its formula. The raw fruit and vegetable blend offers additional nutrients and antioxidants that enhance reproductive function, while the probiotic blend positively impacts overall wellness. Another added benefit is the formula is delivered via cold-pressed chia seed oil. Chia seeds are high in antioxidants and omega-3 fatty acids, which may both be beneficial for fertility. (10, 27)
Garden of Life is dedicated to providing high-quality, pure supplements. Just take a look at a few of their numerous certifications:
- OU Kosher Certified
- NSF Gluten-Free Certified
- Informed-Choice Certified
- PETA Cruelty-Free & Vegan
- Certified USDA Organic
This supplement contains no gluten, is vegan, and is free of GMOs. It’s safe to say Garden of Life has you covered if you have any dietary restrictions.
The price point is higher compared to other competitors. However, you may find that the superior quality justifies the greater price of $0.65 per serving. One serving is one capsule, which means each bottle should last 60 days. It’s recommended to take this supplement daily with food. The capsules are unflavored, so there should be no unpleasant aftertaste. However, some reviewers noted that the capsule’s size and texture made swallowing difficult.
One downside to note is that many customers reported gastrointestinal discomfort. This is likely due to the probiotic blend, which is known to cause symptoms like gas or bloating. However, these symptoms should resolve within the first few days but may last up to two weeks.
If the price point seems daunting, you can buy one bottle to begin. No subscription service is required. However, if you decide you want to continue taking this supplement long term, you can subscribe and save with Amazon Prime and receive your orders at your selected frequency.
What our experts say
“CoQ10 can be helpful for women trying to conceive, especially women over the age of 35,” according to Dr. Aneesha Dhargalkar, MD. “The antioxidant properties mentioned above mean that CoQ10 improves egg and sperm quality. It also may thicken the uterine lining, creating an ideal environment for embryo implantation.”
“CoQ10 is a powerful antioxidant found in high energy cells like the ovaries and sperm,” adds Dr. Dawoodbhoy. “Preliminary studies, as there are minimal studies on CoQ10, have shown that it improves egg and sperm quality by reducing inflammation in the body. However, without enough research, it is hard to say definitively if there is enough benefit in taking this supplement and the adequate time period to take it to ensure results.”
What customers are saying
Many Amazon customers are impressed with the quality of the supplement.
“There are quite a few reasons why I love this product. It’s raw, gluten-free, and suitable for vegetarians! But it doesn’t stop there. It has no binders— a rare find in supplements these days. The antioxidant support is a fantastic bonus. Plus, it supports cardiovascular function and is a staple in my health regimen.”
Melissa, verified Amazon buyer
Another verified Amazon buyer, Nancy M., reports similar feelings. She writes, “This is a positive review because the product has many great qualities. It’s vegetarian and dairy-free, which is perfect for my dietary needs. Plus, the supplement promotes digestive comfort and healthy elimination. It’s a wonderful addition to my daily routine, and I highly recommend it!”
While many customers appreciate the health benefits of this supplement, some customers report the pills are sticky and hard to swallow. Verified Amazon buyer “One in 200 Thousand” states, “Received bottle and pills stuck together, with what looked like cotton stuck to it.”
This could be a quality control issue that would warrant a call to customer service.
Specs
| Form | Capsule |
| Daily dose | One capsule |
| Third-party tested | Yes |
| Number of servings | 60 |
| Price per serving | $0.65 |
How we score fertility pills and supplements
Our scoring methodology for fertility pills is designed to thoroughly evaluate the safety, efficacy, and value of products intended to support reproductive health. Each fertility supplement is assessed across several key categories to ensure consumers can make informed decisions based on quality, transparency, and performance. Here’s how we evaluate fertility pills:
Ingredient quality and effectiveness — 40%
- Clinically proven ingredients: We prioritize supplements that contain ingredients backed by clinical research to improve fertility, such as folic acid, myoinositol, CoQ10, and other essential vitamins and minerals. Products that use science-backed ingredients at clinically effective dosages are awarded higher scores.
- Purity and sourcing: Fertility pills and supplements that use high-quality, clean, and sustainably sourced ingredients, free from harmful additives, fillers, or artificial substances, receive higher ratings.
- Third-party testing: Products that undergo third-party lab testing for purity and potency, ensuring the absence of contaminants, are scored more favorably.
Formulation and bioavailability — 25%
- Optimal absorption: The bioavailability of ingredients, or how well the body absorbs them, is critical. Pills that use enhanced delivery systems, such as micronized or liposomal formulations, for better absorption are rated higher.
- Balanced formulation: We assess the balance of ingredients, ensuring that the formula provides comprehensive reproductive support without overwhelming the body with excessive dosages or unnecessary ingredients.
Efficacy and results — 20%
- Consumer feedback: We consider real-world user reviews and testimonials regarding the supplement’s effectiveness in supporting fertility. Positive results related to menstrual regularity, ovulation, and overall reproductive health are factored into the score.
- Clinical support: Products that have clinical trials or studies supporting their effectiveness for fertility enhancement are given additional weight in the efficacy category.
Cost and value — 10%
- Price per serving: We analyze the price of the supplement relative to its ingredients and effectiveness.
- Service size and supply: The number of servings per container and the length of a single purchase are considered, as well as whether multiple pills are required daily to achieve the desired effect.
Brand reputation and transparency — 5%
- Manufacturer’s credibility: The brand’s history, reputation, and commitment to reproductive health are key factors in determining our score in this category.
- Transparency: We value companies that are transparent about their ingredients, manufacturing processes, and testing protocols. Clear labeling and readily available information about the product’s development and sourcing enhance the score.
Overall scoring
Each fertility pill is scored on a scale of 1 to 5 in each category above, with the scores weighted according to their significance. These scores are then averaged to create a final overall rating on a scale of 1 to 5, with 5 representing the highest-quality fertility supplement in our review.
What are fertility pills?
Fertility pills are drugs or supplements that aim to boost fertility and increase the likelihood of conception. They may be prescription drugs or over-the-counter (OTC) supplements. Each contributes to women’s reproductive health in unique ways.
The US Food and Drug Administration (FDA) approves prescription reproductive drugs. These drugs have been rigorously tested and must be administered under the guidance of a healthcare expert. Prescription reproductive medicines include clomiphene, letrozole, metformin, and tamoxifen.
OTC fertility supplements are available online or in stores and do not require a prescription from a physician. While the FDA oversees fertility supplements to ensure they are properly made and labeled, it does not approve them for safety or efficacy. OTC fertility supplements include folic acid, CoQ10, omega-3 fatty acids, and prenatal vitamins.
These drugs and supplements aim to regulate hormones, improve egg quality, and promote general reproductive health.
Your age determines the type of fertility pill you should take, underlying health issues, and specific fertility challenges.
How to choose the best fertility pill or supplement to get pregnant
Choosing the best fertility pill to get pregnant will depend on factors such as your health status, overall reproductive goals, and any fertility challenges. Here’s a guide to help you make the best choice:
Consult with your healthcare provider
It’s important to be aware of any underlying fertility issues before taking fertility supplements. Consult with your healthcare provider to ensure you receive appropriate diagnoses.
Once your doctor has a better picture of your reproductive health, they can make personalized recommendations, which may include a prescription fertility medication or an OTC fertility supplement.
Consider your lifestyle and preferences
Select supplements that fit your lifestyle if you have any dietary requirements or preferences, such as being gluten-free, vegetarian, or vegan. Many supplements come in these formulations but be sure to read the product descriptions carefully.
Evaluate the quality of the supplement
Look for supplements that are third-party tested for purity and potency. Certifications like United States Pharmacopeia (USP) or National Sanitation Foundation (NSF) indicate high manufacturing standards.
Inspect the ingredient list carefully and avoid supplements that include unnecessary additives or fillers.
Monitor and adjust
Track your progress closely once you start taking a fertility pill. Monitor your menstrual cycle, ovulation, and any side effects.
Report your findings regularly to your healthcare provider to ensure adjustments are made in a timely manner if needed. Your physician may also recommend routine blood work to monitor your levels and overall health.
What to look for in a fertility pill or supplement
When choosing a fertility pill or supplement, there are several factors to consider. In addition to the tips given above, here’s what to look for when selecting specific fertility pills and supplements:
Prenatal multivitamin
A prenatal multivitamin should include enough vitamins and nutrients to support you and your baby.
Pick a prenatal multivitamin that includes the following: (18)
- Calcium: 1000 mg
- Choline: 450 mg
- DHA: 200-300 mg
- Folic acid: 400 mcg
- Iodine: 220 mcg
- Iron: 27 mg
- Vitamin A: 770 mcg
- Vitamin B6: 1.9 mcg
- Vitamin B12: 2.6 mcg
- Vitamin C: 85 mg
- Vitamin D: 600 IU
- Zinc: 15 mg
Omega-3 supplement
Omega-3 fatty acids support reproductive hormones and are vital for fetal brain development. Select a supplement that offers 200-300 mg of DHA and EPA at minimum.
Folic acid supplement
Folic acid plays a critical role in promoting fetal development and preventing neural tube abnormalities. At least one month before conception, start taking a supplement containing 400–800 mcg of folate or folic acid and continue taking it until at least 12 weeks. The neural tube closes at 12 weeks, but it’s still recommended to take folic acid throughout your entire pregnancy. (24)
Vitamin D supplement
Higher amounts of vitamin D have been associated with better reproductive results. Choose a vitamin D3 supplement that has between 1,000 and 2,000 IU.
CoQ10 supplement
CoQ10 is a powerful antioxidant that protects eggs from oxidative stress. Look for a supplement that contains 100-200 mg of CoQ10.
FAQs
Which supplement is best for fertility?
The best supplements for fertility include prenatal vitamins, folic acid, CoQ10, vitamin D, and omega-3 fatty acids. Each of these supplements provides important nutrients that support fertility and hormonal imbalance. However, the best supplement for fertility will depend on your reproductive needs.
What is the strongest over-the-counter fertility pill?
CoQ10 is one of the most potent OTC fertility pills due to its ability to improve egg quality and overall reproductive health. (18) Other strong options include vitamins with methylated folate and omega-3 fatty acids.
How long does it take to get pregnant with fertility pills?
Most couples will get pregnant within a year, but this timeline is affected by overall health and age. (14) Fertility supplements may take a few months to show results as they work gradually to improve egg quality and support overall reproductive health.
Do fertility pills really work?
The effectiveness of fertility pills will depend on your underlying fertility issues. For instance, a complex fertility issue like polycystic ovary syndrome (PCOS) requires more in-depth management than OTC supplements can provide. However, supplements like folic acid and CoQ10 are important in supporting fertility.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases.
Our experts
Dr. Aneesha Dhargalkar
Dr. Aneesha Dhargalkar is a board-certified emergency medicine physician currently practicing in West Chester, PA. She graduated cum laude from John Hopkins University in 2002 and from Jefferson Medical College in 2006. After this, Dr. Dhargalkar attended and completed a three-year residency program in emergency medicine at Temple University Health System. Dr. Dhargalkar is the director of her hospital’s wellness provider program and sits on the executive board of both the Chester County Suicide Prevention Task Force and the Unionville Chadds Ford School District Education Foundation.
Dr. Fatema Dawoodbhoy, MBBS, BSc
Dr. Dawoodbhoy MBBS BSc (she/her) is an Academic Doctor working in London with a keen interest in Obstetrics & Gynaecology. She is a double graduate from Imperial College London with an MBBS and a BSc in Business Management (First Class Honours).
Heather Morsellino
Heather Morsellino is a freelance writer and fact-checker with over four years of experience in healthcare. She has worked as a pharmacy technician, emergency room medical scribe, and anesthesia technician in the operating room and will finish her ADN within the following year.
Holly Myers, RN, BSN
Fortune Recommends Health Writer
About Author
Holly Myers is a freelance health writer with over seven years of healthcare experience in a variety of healthcare settings. Her specialties that she has worked closely with in her nursing career include oncology, bariatrics, gynecology, urology, orthopedics, and hospice and palliative care. Holly created a nursing website that focuses on nursing education. She has created many study guides, cheat sheets, and flashcards to help nursing students achieve their nursing career goals.