Median human lifespans and health spans are increasing due to technological advances, diet, exercise, and medicine. This is evidenced by the number of centenarians nearly doubling every ten years. (1) The growing interest in Nicotinamide mononucleotide supplementation for increasing life expectancy stems from longevity research and influence through internet access.
Nicotinamide mononucleotide, or NMN, is a naturally occurring molecule and precursor to nicotinamide adenine dinucleotide, shortened to NAD or NAD+. NAD is a coenzyme that may directly and indirectly influence many key cellular functions, including DNA repair, immune cell function, and metabolic pathways. (2) Additionally, studies have shown that boosting NAD+ levels reverses mitochondrial dysfunction, increases insulin sensitivity, and extends lifespan. However, NAD levels plummet to around half by middle age, and studies show that the body prefers to utilize NMN to make NAD rather than use NAD from direct supplementation. This is the reason why getting the right NMN supplement is essential.
“In June 2018, the World Health Organization added aging to its International Classification of Diseases. Aging is now recognized as a disease in and of itself,” says Dr. Aneesha Dhargalkar, MD. “As we know, aging can also lead to other serious medical diagnoses, including cancer, cardiovascular disease, and neurologic conditions such as stroke and dementia. Increases in the enzyme of NAD+ have been found to enhance survival. Taken orally, NMN easily converts to NAD+. Therefore, theoretically, the use of this supplement to decrease aging makes sense. However, there is minimal data on the actual efficacy of this supplement, as well as its safety and side effects. Anyone taking an NMN supplement should be fully aware of these limitations.”
We know that your life and health are invaluable, so proper precaution is crucial when putting something on or in your body. It’s often a hassle to comb through online stores, reviews, and web pages to find trusted sources. As such, we went through a meticulous process to find the best NMN supplements available today. Our medical and certified experts effectively put in the work so you can choose the NMN supplement that works best for you.
Editor’s choice
Nutricost NMN is our top pick for its straightforward formulation, affordability, and focus on quality. With 500mg of pure NMN per capsule, it supports NAD+ production, which is essential for cellular energy, DNA repair, and overall health. Priced at $33.95 for a 60-capsule bottle, it offers excellent value for those looking to enhance their health and longevity without breaking the bank.
Medical disclaimer: This article is intended for educational and informational purposes only. It is not intended as a substitute for medical advice. For health advice, contact a licensed healthcare provider.
Our picks for the best NMN supplements
- Best value: Nutricost NMN
- Most pure: partiQlar Pure NMN
- Best vegan: Wonderfeel Youngr™ NMN
- Best powder: ProHealth NMN Pro Powder 30G
- Best with Resveratrol: Omre NMN + Resveratrol
- Best liposomal: GenuinePurity Liposomal NMN
- Best quality: Lifeforce Peak NMN
- Best NMNH: Doublewood NMNH Supplement
Compare NMN supplements
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| Nutricost NMN | PartiQlar Pure NMN | Wonderfeel Youngr™ NMN | ProHealth NMN Pro™ Powder | Omre NMN + Resveratrol | GenuinePurity Liposomal NMN | Lifeforce Peak NMN | Doublewood NMNH Supplement | |
| Rating | ||||||||
| Price | $33.95 per bottle | $64.99 – $254.94 individually, $58.49 subscription | $88 individually, $73 subscription *introductory price | $44.25 per pack | $59 individually, $56 subscription | $79 a bottle | $100 individually, $80 subscription | $59.89 a bottle |
| Key ingredients | Nicotinamide Mononucleotide | Nicotinamide mononucleotide | Nicotinamide mononucleotide | Uthever (β-Nicotinamide mononucleotide) | NMN and resveratrol | Nicotinamide mononucleotide | Berberine HCl, NMN, white mulberry extract, Lithium Orotate, Spermidine | NMNH (Dihydronicotinamide Mononucleotide) |
| Dosage | Two a day | One a day | Two a day | 1 level scoop | Two a day | One a day | One a day | Two a day |
| Form | Capsule | Capsule | Capsule | Powder | Capsule | Capsule | Capsule | Capsule |
Best value NMN supplement: Nutricost NMN
Key product features
What you should know
Nutricost NMN is a high-quality NMN supplement designed to support NAD+ production, promoting cellular health and energy. (2) It’s an affordable option compared to other NAD+ boosters, offering a straightforward formulation focused on effectiveness and value.
- Nutricost NMN is available at $33.95 for a 60-capsule bottle, with each serving providing 500mg of NMN for a one-month supply.
- Made in a GMP-compliant facility, Nutricost NMN follows strict quality standards, which helps ensure a pure and effective product.
- Each 250mg capsule is made with non-GMO ingredients and is third-party tested for quality and purity, ensuring a trustworthy supplement.
Why we like Nutricost NMN as best value
Nutricost NMN is a popular and budget-friendly option within the NAD+ supplement market, helping to boost cellular health and energy. Unlike some of its more expensive competitors, Nutricost NMN focuses on NMN (Nicotinamide Mononucleotide) as its sole active ingredient.
NMN is a direct precursor to NAD+, a coenzyme essential for various cellular functions, including energy production, DNA repair, and overall cellular resilience. (2) By supplementing with NMN, users may experience increased NAD+ levels, which are linked to potential benefits like improved metabolic function, enhanced cognitive performance, and healthier aging. (2)
Nutricost NMN is available in a 60-capsule bottle, with each capsule delivering 250mg of NMN, for a daily total of 500mg. Priced at $33.95, this product provides a one-month supply when taken daily. This pricing structure makes it accessible for those interested in NMN supplementation but wary of the higher price tags often associated with branded products. Nutricost’s transparent pricing strategy, combined with third-party testing and production in a GMP-compliant facility, provides confidence in the product’s quality and effectiveness.
The formula contains non-GMO ingredients and is free from unnecessary additives or fillers. The product is also third party tested by ISO-accredited laboratories.
Nutricost offers free shipping over $59, meaning you’d have to pay for shipping if you only purchase this product on the site. The Subscribe & Save feature will save you 20%, making it $27.16. Even though you’ll still have to pay for shipping, the money saved might make up for the extra shipping cost.
If you end up not liking your product, Nutricost offers a 60-day money back guarantee for a 100% refund. However this doesn’t include shipping fees. While this is a great policy, it’s important to note that it may take longer than 60 days to see results. You can call or send Nutricost an email at support@nutricost.com with any and all questions or concerns related to any product and service.
For consumers who prioritize cost-effectiveness and simplicity, Nutricost NMN is a worthwhile consideration. Nutricost NMN is well-suited for individuals looking for an accessible, no-nonsense NAD+ booster.
Specs
| Serving size | Two a day |
| Servings per container | 30 |
| Dose per serving | 500mg |
| Active ingredients | Nicotinamide Mononucleotide |
| Other ingredients | Rice extract blend, hypromellose capsule |
| Purity percentage | N/A |
| Order quantity options | Unlimited |
Best pure NMN supplement: PartiQlar Pure NMN
Key product features
What you should know
PatiQlar Pure NMN is among the supplements with the highest NMN purity available in the market, with a purity of 99%. A higher purity concentration allows for safer oral administration and increased effectiveness.
- PartiQlar’s website provides extensive information about its NMN supplements, including ingredient lists, the company’s NMN source, and a FAQ section.
- The cost depends on bottle quantity and whether a subscription is purchased, with the lowest and highest subscription prices being $65 and $255, respectively.
- PartiQlar Pure NMN supplements are a sure fit for customers who want to be confident in the safety and effectiveness of their purchases.
Why we like PartiQlar Pure NMN as best pure NMN supplement
Many top manufacturers offer capsules and powders of NMN with 98% purity, while others may provide supplements with 80% purity or lower. PartiQlar offers NMN supplements that contain stabilized NMN with a purity of 99%. PartiQlar Pure NMN provides a verifiable named source for their raw NMN supply.
Research has shown that dietary supplements for sports could lead to unintended doping because of contamination. Moreover, a 12%- 58% contamination rate occurs in nutritional sports supplements, depending on the country. (3) Such research emphasizes the importance of proper labeling, certifications, and good manufacturing processes for all supplements, regardless of purpose, including NMN.
Contaminants may cause unintended side effects and diminish the effects of a supplement’s active ingredients. ParitQlar’s high-priority focus on safety and purity for their products means users have improved chances to receive all the benefits NMN offers. According to the brand, customers may experience:
- Energy boosts
- DNA repair (of mutations)
- Improved insulin sensitivity
- Improved aerobic strength
- Strengthened skeletal muscles
- Better memory and recollection
- Improved cognitive function
Knowing what is entering your body is imperative, especially when health and longevity are concerned. We appreciate that PartiQlar proudly declares on its website that Effepharm, a Chinese-based product supplier, is the source of its raw NMN. PartiQlar’s manufacturing facilities are GMP (Good Manufacturing Practice) certified and FDA-registered, and its products are third-party tested and made in the USA. This information should reassure those aiming to improve their health and wellness. Moreover, downloads of the quality reports are available online.
Understanding where your supplements are sourced from and if the ingredients are properly labeled helps prevent issues with supplementation. Lower-quality supplements may contain fillers, synthetic ingredients, or contaminants, which could have terrible outcomes. Any of these factors may inflict illnesses, induce addiction, reduce supplement effectiveness, or cause additional side effects. Dietary supplements are not drugs and don’t go through the FDA’s approval process.
Each bottle of Pure NMN comes with 60 capsules, which PartiQlar states is a two-month supply. Consequently, a daily dose is one 500 mg capsule. Buyers can purchase one, three, or six bottles, which equals a two-month, six-month, and twelve-month supply, respectively. Additionally, a one-time purchase is optional, or buyers can subscribe and save an extra 10% off any tier.
What customers are saying
123 Trustpilot reviews rate PartiQlar as an “excellent” vitamin and supplement store with an average rating of 4.6/5 stars. The general sentiment is praise for PartiQlar’s great service and that its products are effective and of high quality.
“So far so good. I keep reordering mainly because it seems to be doing some good. I’m still evaluating, but there are slight improvements in sleep, focus, and overall well-being.”
Stephen L., Verified Trustpilot reviewer
NMN helps provide the body with the resources to perform many functions, as the previous reviewer experienced. Some reviewers gave specific examples of how Pure NMN surprised them.
An anonymous Trustpilot user, “Customer,” expressed satisfaction with Pure NMN’s management of their wife’s menopause. Their five-star review read, “My wife’s nightly hot flashes have decreased within two weeks of starting NMN 500 mg once a day. She has been using it for a month. No other supplements have helped.”
Some users didn’t share the same 5-star experiences, with many receiving little to no benefit from PartiQlar’s products.
Trustpilot user Chee P. was not pleased with their purchase and noted no visible improvements. The 1-star review detailed, “I have taken this for six months. However, I don’t see any improvement. I find my eyesight worsens, and gray hairs grow much more. I really wasted my money.”
Specs
| Serving size | One a day |
| Servings per container | 60 |
| Dose per serving | 500 mg |
| Active ingredients | Nicotinamide mononucleotide |
| Other ingredients | Vegetable cellulose capsule |
| Purity percentage | 99% |
| Order quantity options | One, three, or six bottles |
Best vegan NMN supplement: Wonderfeel Youngr™ NMN
Key product features
What you should know
Youngr™ NMN supplements have a patented vegan formula created by Havard scientist and physician Andrew Salzman. Youngr™ NMN is specially designed to help repair cellular functionality and protect cells from damage.
- Each vegan-safe capsule contains a large 450 mg dose of NMN, and the two-times-daily dosage means users get a whopping 900mg of NMN into their system.
- First-time buyers receive $10 off for introductory prices and pay $88 for individual purchases and $73 zwith a subscription
- Youngr™ NMN is for customers who don’t mind spending money on a trusted, science-backed, patented NMN supplement.
Why we like Wonderfeel Youngr™ NMN as best vegan NMN supplement
Other NMN supplements claim to be safe for vegan and vegetarian lifestyles. However, Youngr™ NMN tops our list as the best vegan NMN supplement because it has a patented vegan-friendly formula by licensed physician and scientist Dr. Andrew Salzman.
The Youngr™ NMN pill contains NMN, ergothioneine, trans-resveratrol, olive fruit extract, and vitamin D3, all held by a vegetable cellulose shell. We appreciate the comfort of knowing a visible scientific face is behind Youngr™ NMN’s manufacturing, not just a company selling a product.
Wonderfeel recommends taking two Youngr™ NMN capsules at any time of day. Each pill contains 450mg of NMN, resulting in a daily dosage of 900mg. A 900mg dose is higher than the typical 100-350mg range of other supplements. However, 900mg is generally well-tolerated by the body when taken orally. Individuals may see and experience beneficial results in about two weeks. (4)
Wonderfeel NMN is over 99% pure. Every batch of Wonderfeel products are third-party tested, and the third-party tests come with a QR code so the viewer can verify the results on the certified labs website. You can view them on the website here and here.
WonderFeel backs its dosage amount using a study based on several SF-36 answers over two months. SF-36 is a questionnaire that relies on answers based on personal experiences and feelings to get a health score. The study WonderFeel uses claims that customers using 900mg had the highest health score over the two months. (5)
Many might find Youngr™ NMN’s prices deterring, considering one-off and monthly subscription costs are $98 and $83, respectively. Fortunately, introductory pricing takes $10 off each price and helps to mitigate any expenditures. A year’s total cost of individually purchased Youngr™ NMN is $1,056, while a subscription costs $996.
Interested parties may reduce costs by lowering their dosage to one Youngr™ NMN supplement daily. A one-daily dose cuts the daily NMN value to 450mg but lengthens the supply to 60 days. Taking one Youngr™ NMN pill daily could save money; a single bottle can last two months. Any dose changes should involve first talking with a healthcare provider.
Specs
| Serving size | Two a day |
| Servings per container | 60 |
| Dose per serving | 900mg |
| Active ingredients | Nicotinamide mononucleotide |
| Other ingredients | Ergothioneine, olive fruit extract, vitamin D3 |
| Purity percentage | 99% |
| Order quantity options | Unlimited |
Best powder NMN supplement: ProHealth NMN Pro™ Powder
Key product features
What you should know
ProHealth NMN Pro™ Powder is a pure NMN supplement designed to enhance cellular health and boost NAD+ levels, which are essential for energy production and healthy aging. (7) NMN (nicotinamide mononucleotide) is a molecule that supports cellular function and helps maintain the body’s metabolic processes. (6)
- Customers can purchase one bottle for $79.80 or save 20% with Subscribe & Save, which would update the price to $55.86.
- This is best for people focused on improving their longevity, cognitive function, and metabolic health. (7)
- ProHealth NMN Pro™ Powder is made with pure NMN and contains no additives or fillers, making it one of the most potent options for optimizing NAD+ levels.
- Depending on personal usage patterns, subscriptions can be ordered at intervals ranging from 30 to 90 days.
Why we like ProHealth NMN Pro™ Powder as best powder
ProHealth NMN Pro™ Powder stands out for its purity, making it a top choice for anyone looking to boost NAD+ levels and support healthy aging. This powder contains 1000 mg of 100%pure NMN, offering a direct and high-quality approach to increasing cellular energy and promoting longevity.
We appreciate that ProHealth focuses solely on NMN in this formulation, ensuring that users receive the highest quality NMN without unnecessary fillers or additives. According to ProHealth, in a peer-reviewed, double-blind, placebo-controlled, published clinical study, ProHealth’s NMN is the only clinically proven NMN to boost NAD+ levels. Results of the study indicated a 38% increase in NAD+ levels and a 12-year reversal in biological age. However, we were unable to find the study to confirm these results.
One key reason we favor ProHealth NMN Pro™ is its flexibility in dosage. As a powder, it allows users to measure and adjust their intake based on their needs, offering greater control compared to pre-measured capsules. This can be particularly helpful for those mindful of their dosage or prefer to start with smaller amounts and gradually increase.
NMN is a critical precursor to NAD+, a molecule involved in numerous cellular functions, including energy production, DNA repair, and metabolic regulation. (2) Increasing NAD+ levels through NMN supplementation has been linked to improved cognitive function, physical endurance, and overall vitality. (8) ProHealth, by offering a pure NMN supplement, provides a powerful tool for those aiming to enhance their longevity and well-being.
Unlike other NAD+ boosters that combine multiple ingredients, ProHealth NMN Pro™ focuses on a single component. This reduces the risk of potential interactions or complications arising from multi-ingredient formulas.
Additionally, while some supplements may come in capsule form, ProHealth NMN Pro™ Powder is ideal for those who prefer a powder supplement for its versatility and ease of mixing with other beverages or foods. This format also allows for faster absorption, helping users feel the effects more quickly, with one study showing a greater absorption of powder supplements over capsules. (9)
The cost of the product may be a consideration, with a price point around $79.80 for a 30-gram container. However, the potency and flexibility of the powder format may justify the expense for those serious about supporting their longevity goals. Plus, with ProHealth’s reputation for quality and a 30-day money-back guarantee, users can feel confident in their purchase.
For optimal results, ProHealth recommends mixing one scoop of NMN Pro Powder with water or placing it under the tongue once a day. In fact, ProHealth states that placing it under your tongue allows the powder to bypass the gastrointestinal tract, also known as the first pass effect, so it can be absorbed directly into the body. (10)
Specs
| Serving size | One level scoop |
| Servings per container | 30 |
| Dose per serving | 1000mg |
| Active ingredients | Nicotinamide mononucleotide |
| Other ingredients | N/A |
| Purity percentage | >100% |
| Order quantity options | Unlimited |
Best NMN supplement with resveratrol: Omre NMN + Resveratrol
Key product features
What you should know
Omre NMN + Resveratrol is a supplement that blends NMN and resveratrol. It aims to lengthen the user’s health span and life expectancy. Resveratrol is a phytochemical that helps to induce NAD+, while NMN is a molecule used by the body to promote healthy cellular activity.
- Customers can save a minimum of around $36 a year with a committed monthly subscription versus purchasing the supplements independently.
- This is best for people who want to improve their health while taking advantage of Resveratrol’s inflammation-inhibiting properties.
- Subscriptions can be ordered every month to every six months (180) days. This can be cost-effective for those who take the supplements every few days.
- Each supplement contains approximately 98% pure NMN and resveratrol.
Why we like Omre NMN + Resveratrol as best with resveratrol
Omre makes maximizing longevity goals convenient and simple by providing NMN and resveratrol in a daily-dose capsule. We like that Omre lists the ingredients, their amount, and each ingredient’s purpose for clarity.
Combining these two pro-longevity chemicals helps set Omre NM + Resveratrol apart from other supplements. The ingredients work together to help increase the body’s NAD levels. It’s a holistic and effective method to potentially improve longevity and wellness on a macro level through micro-processes.
Omre NMN + Resveratrol is best taken with fat-rich foods to maximize results. This is because resveratrol is fat-soluble and is absorbed by the body better in the presence of fats. Conversely, NMN is absorbed regardless of what it’s taken with. The body has transporter proteins, also “carriers,” that bring the chemical into the cell. (11)
Nicotinamide mononucleotide is the supplement’s main key ingredient. It’s a tiny chemical that cells can effectively take in and convert into NAD. The newly formed NAD may be used to repair cellular DNA, restore cellular functions, and improve mitochondrial metabolism. (12)
Resveratrol is a phytochemical that is often used to combat inflammation. Moreover, studies show that it may have cardioprotective, neuroprotective, antimicrobial, and anticancer properties, possibly making it a valuable chemical in the longevity community. (13) It’s a naturally occurring antioxidant in red grapes, berries, and wine. Omre mainly included resveratrol since studies show it increases sirtuin activity, which upregulates NAD production. (14, 15)
The Omre NMN + Resveratrol capsules have a vegetable cellulose casing containing the powdered ingredients. People who prefer tablet and chalk-like pills may consider purchasing a different pill altogether. However, we found that NMN supplements mostly come in capsule form and that resveratrol can come in tablet form. Finding a singular tablet that contains both ingredients may prove difficult.
According to one study, oral supplementation of 600mg of NMN provided the highest blood NAD concentrations and showed the best physical activity performance. (4) The Omre recommended two-capsule dosage is 500mg, which is 100mg shy of the reported optimal dosage. Moreover, taking one capsule a day may address resveratrol’s potential short-term side effects.
The supplements may be cost-prohibitive because an individual purchase price is approximately $60. However, some may see the value in paying the cost of two mid-tier supplements for a little over the price of one. Users generally feel results in about two weeks of taking NMN, and a 30-day money-back guarantee with shipping is included in case buyers are unsatisfied.
Taking one supplement daily rather than the suggested two saves on costs and can still benefit a customer’s longevity. One pill contains 250mg of NMN, which can still be an effective dose amount. Importantly, it is best to talk to a health practitioner before changing a dosage.
Specs
| Serving size | Two a day |
| Servings per container | 30 |
| Dose per serving | 500mg |
| Active ingredients | Nicotinamide mononucleotide, resveratrol |
| Other ingredients | BioPerine, vegetable cellulose capsule |
| Purity percentage | 98% |
| Order quantity options | One, two, three bottles |
Best liposomal NMN supplement: GenuinePurity Liposomal NMN
Key product features
What you should know
Genuine Purity’s Liposomal NMN supplement is designed to promote healthy aging by boosting NAD+ levels and supporting cellular energy. (2) Its advanced liposomal delivery system ensures superior absorption compared to traditional NMN supplements. (16)
- Liposomal technology increases bioavailability, allowing for more efficient delivery of NMN into the bloodstream. (16)
- It may boost NAD+ levels to help promote cellular repair, energy production, and overall longevity. (2)
- The supplement is made with non-GMO ingredients, free of synthetic additives, and designed for optimal effectiveness.
- You can save up to $120 by ordering six bottles, totaling $354. However, you can just purchase one bottle for $79.
Why we like GenuinePurity Liposomal NMN as best liposomal
Genuine Purity’s Liposomal NMN supplement offers a unique approach to supporting healthy aging by enhancing NAD+ levels. It uses advanced liposomal delivery technology for better absorption and bioavailability. (16) Unlike traditional NMN supplements, the liposomal form increases nutrient uptake efficiency, ensuring that your body gets the most out of each dose. (16) This makes it ideal for those seeking a low-dose NMN solution without compromising effectiveness.
Each bottle provides 250mg of NMN per serving, a lower dose than some alternatives but sufficient to promote cellular repair, energy production, and longevity. (6) The product is also made with non-GMO ingredients and is free of synthetic additives, focusing on purity and safety for its users. The liposomal delivery system encases the NMN in a lipid layer, allowing it to pass more easily through the digestive system and into the bloodstream, ensuring superior absorption compared to standard supplements. (16)
For optimal use, Genuine Purity recommends taking one dose per day, ideally with food, to maximize absorption and promote better cellular health. The supplement is suitable for those looking to improve energy levels, cognitive function, and general well-being while using a lower dose to maintain a more gradual but consistent NAD+ boost. (2)
You can purchase one bottle on the brand’s website for $79, although it’s typically on sale for $69. If you choose to purchase three bottles, you can save $42, totaling $237. If you choose six, you can save $120 for $474. If, for some reason, you want to return the product, Genuine Purity offers a 97-day money-back guarantee, which is more generous than other brands on this list. Since it may take a few months to see results, this is a great policy. Just send back the empty container, and the brand will issue you a prompt, hassle-free refund.
Specs
| Serving size | One capsule a day |
| Servings per container | 60 |
| Dose per serving | 250 mg |
| Active ingredients | Nicotinamide mononucleotide |
| Other ingredients | N/A |
| Purity percentage | 98% |
| Order quantity options | One, three, or six bottles |
Best quality NMN supplement: Lifeforce Peak NMN
Key product features
What you should know
Lifeforce Peak NMN is a premium supplement that combines high-quality NMN with several other key ingredients to help increase NAD+ levels and support cellular energy production.
- Lifeforce’s website provides useful information about its NMN supplements, including what NMN may be able to do for your body and specific biomarkers.
- You can save $20 by opting for the monthly subscription, lowering the cost of the supplement to $80.
- Some users may experience mild to moderate side effects (most common are nausea, mild headache, jitteriness, or disturbance in sleep/wake cycle) with a higher dose, so Lifeforce recommends starting with one capsule daily.
Why we like Lifeforce Peak NMN as best quality
Lifeforce Peak NMN is a high-quality nicotinamide mononucleotide (NMN) supplement designed to enhance cellular health, support longevity, and promote optimal metabolic function. (6) NMN is a precursor to NAD+ (nicotinamide adenine dinucleotide), a critical coenzyme involved in energy production, DNA repair, and cellular regeneration. (2) As we age, NAD+ levels naturally decline, which can contribute to fatigue, cognitive decline, and slower recovery from physical stress. (2) By supplementing with NMN, Lifeforce Peak aims to restore NAD+ levels, offering a wide range of health benefits aimed at combating the aging process.
One of the standout features of Lifeforce Peak NMN is its high purity and quality. The product is third-party tested to guarantee both purity and potency, giving consumers confidence in its efficacy. It is also free from synthetic fillers, artificial preservatives, and other unwanted additives, making it a clean and reliable choice.
Users are advised to take one capsule daily, and increase by one capsule every three days, as tolerated, to reach the recommended three capsules/day. However, this dose may end up being too much for some users, as some report feeling too jittery from the extra capsules. If this happens, lower back to one or two capsules. According to Lifeforce, the supplement works best when taken before lunch or dinner to help your body process carbohydrates.
Each bottle contains 90 capsules, providing a convenient 30-day supply when you reach three capsules a day. The NMN in Lifeforce Peak is designed to be rapidly absorbed by the body, allowing for quick utilization of NAD+ in cells. This increase in NAD+ levels helps boost energy production at the cellular level, promoting improved stamina, cognitive function, and metabolic health. (2) For those focused on maintaining vitality as they age, Lifeforce Peak NMN may offer a scientifically supported method for improving overall wellness.
The benefits of taking NMN may extend beyond simple energy enhancement. By supporting higher NAD+ levels, the supplement promotes better brain function, helping to maintain cognitive clarity and focus over time. (2) It also supports neuroprotective pathways essential for long-term brain health and memory retention. (2) Furthermore, by encouraging DNA repair mechanisms and cellular rejuvenation, NMN may slow down visible signs of aging, such as skin wrinkling and muscle fatigue, while improving the body’s response to stress and inflammation. (2)
NMN is particularly well-suited for those looking to maintain an active lifestyle as they age. Many users report experiencing increased vitality, faster recovery from physical activity, and enhanced endurance. (17) Additionally, it may play a role in heart health, improving cardiovascular function by supporting optimal cellular performance throughout the body. (18)
Specs
| Serving size | One to three capsules a day |
| Servings per container | 90 |
| Dose per serving | 375 mg (for NMN) |
| Active ingredients | Berberine HCl, NMN, White Mulberry Extract, Lithium Orotate, Spermidine |
| Other ingredients | Microcrystalline Cellulose, Hypromellose (capsule shell), Magnesium Stearate, and Silica |
| Purity percentage | 99% |
| Order quantity options | One bottle (monthly or one-time) |
Best NMNH supplement: Double Wood NMNH Supplement
Key product features
What you should know
Double Wood’s NMNH (Dihydronicotinamide Mononucleotide) supplement is designed to support healthy aging by boosting NAD+ levels, which naturally decline as we age. (2) It offers a good alternative to traditional NMN supplements.
- Each serving provides 250mg of NMNH to effectively increase NAD+ production, promoting cellular energy and longevity. (2)
- The supplement is non-GMO, gluten-free, and made without unnecessary additives. It’s also made in the U.S. and third-party tested, ensuring a clean and safe product.
- A single bottle contains 60 capsules, offering a 30-day supply when taken as directed.
Why we like Double Wood NMNH Supplement as best NMNH supplement
Double Wood’s NMNH (Dihydronicotinamide Mononucleotide) supplement is an advanced alternative to traditional NMN, designed to enhance NAD+ production and support healthy aging. (19) This NMNH supplement is formulated to boost NAD+ levels, offering various health benefits such as increased vitality, improved cognitive function, and cellular rejuvenation. (2) It is one of our top choices for those focused on longevity and energy enhancement.
This product comes with 250mg of NMNH per serving. NMNH may be rapidly absorbed by the body, making it a potentially efficient way to elevate NAD+ levels and, by extension, improve cellular function. (2) In preliminary studies on mice, NMNH has been shown to increase NAD+ levels more quickly than NMN and to a greater extent. (20)
Each bottle contains 60 capsules, providing a 30-day supply when taken at the recommended dosage of two capsules per day. It’s also non-GMO, vegan, and gluten-free, made without synthetic fillers or unnecessary additives, making it an excellent choice for those with dietary restrictions or preferences for pure ingredients.
If you order through Amazon, you can expect the product to arrive in a few days (for Prime members). If you order through Double Wood’s website, standard U.S. shipping normally takes 5-7 business days. Express shipping options are also available. On Amazon, you can buy one bottle for $59.89 or subscribe & save for $53.90. However, on Double Wood’s website, one bottle is available for $47.96 if you subscribe, saving you around 20%.
Double Wood’s NMNH supplement may help increase energy levels, improve mental clarity, and support metabolic health when taken consistently. (2) It may be particularly beneficial for individuals looking to counteract the natural decline in NAD+ as they age, offering support for brain health, cardiovascular function, and physical endurance. (2)
One of the biggest advantages of NMNH over traditional NMN is its potential for better absorption and bioavailability, allowing the body to utilize it more efficiently. Although NMNH is a newer form of NAD+ precursor, early research shows promising results for its effectiveness in supporting cellular health and longevity. (20)
Double Wood Supplements has a 30-day money-back guarantee valid for 30 days after the product is delivered. However, it’s important to note that this may not be enough time to know if the product is effective, making the 30 days inconvenient. You can contact customer service, and one of the representatives will assist you in returning the product.
What customers are saying
Double Wood’s NMNH supplement has over 200 reviews on Amazon, with an average rating of 4.4 out of 5 stars, with customers praising its effectiveness and quality.
“Be prepared to have your energy and overall wellness increased. Love love love this,” gloats an Amazon customer with the username “lake girl.”
One Amazon customer, Mia Brinkley, noticed an improvement in their skin, stating, “I wanted to give this product a few months to ensure I wasn’t seeing what I wanted to see! I am 44, and I have noticed a huge difference in the texture of my skin. I have received quite a few compliments regarding the glow and smoothness.”
Doug Wilks, an Amazon customer, reiterates the lack of research. “ It seems to be effective. Sleep quality is better than when on NMN. More studies are needed on the effects of this product on cells and its safety. However, it’s more readily available than NMN,” they say.
Specs
| Serving size | Two a day |
| Servings per container | 60 |
| Dose per serving | 250 mg |
| Active ingredients | Dihydronicotinamide Mononucleotide |
| Other ingredients | Hypromellose (capsule), rice flour, vegetable stearate, silica |
| Purity percentage | N/A |
| Order quantity options | One bottle (monthly or one-time) |
Our supplement testing methodology
We assign each product a score of 1 out of 5 for each of the categories we test in, and these scores are then weighted based on importance and averaged to produce a cumulative score out of 5 for each product. One is the lowest rating and five is the highest.
Our overall supplement methodology process is guided by four primary criteria:
Efficacy – 40%
This category assesses whether the supplement delivers on its promised benefits, supported by scientific evidence and clinical studies.
Safety and side effects – 35%
Safety is paramount in our evaluation, and we ensure that supplements offer health benefits without significant risks.
Value – 20%
This category balances cost with the quality and benefits of the supplement.
Customer satisfaction – 5%
Customer satisfaction from purchase to use is a large part of the experience, so we look at the brand’s ability to handle it well.
Considering these, methodologies are developed for specific supplements since they serve distinct purposes, contain varied ingredients, and have unique consumer expectations. Tailoring our evaluation process ensures that each supplement is assessed accurately and fairly, providing consumers with reliable information to make informed decisions.
How to choose the best NMN supplement for you
Choosing the best NMN supplements is a subjective and personal matter involving various considerations. Talking to your healthcare provider will provide greater and more accurate insight into which supplement is the best for you. However, we provided a list of factors to consider before meeting with your healthcare provider or to make a choice on your own.
- Purpose (what do you hope NMN will do for you)
- Form (pill, powder, spray)
- Dose amount
- Raw NMN Source
- Price
- Purity levels (avoid synthetic NMN)
- Manufacturer (research the manufacturer)
- Third-party certifications and testing
NMN supplements are generally safe, but they are not intended for use by children, pregnant women, breastfeeding women, and people taking medications should talk to their healthcare provider before taking NMN supplements. There isn’t enough research to fully understand the effects of NMN supplements on these groups.
Benefits of NMN supplements
NMN supplements offer a considerable number of benefits. Benefits that may result from NMN supplementation include the following (21):
- Improved muscle function
- Increased metabolism
- Increased energy (production)
- Inflammation reduction
- Improved cardiovascular function
- Enhanced insulin secretion and sensitivity
- Improved neurological function
Studies have shown that mice supplemented with NMN experienced increased metabolism, improved eye function, enhanced physical activity, improved insulin sensitivity, improved mitochondrial metabolism, and suppression of age-linked changes in gene expression. (22) It is believed humans share some of these kinds of benefits. More research must be done to produce a more defined list of benefits.
“Limited data exists on the use of NMN supplements in humans. One study of forty-two men over or equal to 65 years of age found that a 12-week daily NMN supplementation was safe, well-tolerated, and increased NAD+ levels. (23) A second study of 108 participants given NMN daily for twelve weeks found enhancements in lower limb mobility and decreased sleepiness in adults. (7) These are two of the main studies regarding NMN supplements—there are very few additional studies evaluating their effectiveness and safety in humans.” states Dr. Dhargalkar.
Potential NMN supplement side effects
Side effects of NMN supplementation are considered rare and are generally mild if they occur. Doses of up to 900mg are usually well tolerated by the body, and some studies have seen tolerance to doses as high as 2000mg daily. Not everyone experiences adverse effects, particularly at lower doses. (4)
Potential side effects of NMN are:
- Headaches
- Diarrhea
- Nausea
- Indigestion
- Fatigue
NMN vs NAD supplements
NMN and NAD supplements both aim to support cellular energy, DNA repair, and overall health by increasing NAD+ levels. However, there are significant differences between the two, particularly in terms of how the body absorbs and utilizes each compound.
NMN and NAD supplements are similar because NMN is the precursor to NAD and is involved in the same biological functions at a cellular level. However, studies suggest that NAD is a larger chemical and not used as effectively as NMN is by the cells for upregulated levels of NAD. (24)
When NMN is ingested, the body readily converts it into NAD+. Because NMN is a smaller molecule, it can enter cells more efficiently and ultimately boost NAD+ levels in a way that’s more accessible for cellular processes. (2) Research indicates that NMN supplementation can effectively raise NAD+ levels and support healthy aging, metabolism, and other cellular functions. (2)
NAD+ is a larger and more complex molecule. When taken as a supplement, NAD+ itself is not as readily absorbed by the cells, as it often breaks down into smaller components during digestion. (6) As a result, NAD+ supplements may not directly increase NAD+ levels as effectively as NMN. (6) NAD+ molecules struggle to cross cell membranes due to their size, which limits their direct utility within the cells where NAD+ is most needed. (6)
Research has shown that NMN supplements may promote NAD+ production in a more targeted and efficient way. (4) By boosting NAD+ levels, NMN helps support key processes like sirtuin activation, mitochondrial function, and cellular repair. NAD+, on the other hand, is typically broken down into precursors like NMN or NR (nicotinamide riboside) during digestion, which the body then uses to increase NAD+ indirectly. (4,6)
NMN vs resveratrol
While NMN and resveratrol are both popular supplements known for their potential anti-aging benefits, they function quite differently at the cellular level. While both aim to support cellular health and longevity, their mechanisms of action and primary benefits vary significantly.
As mentioned, NMN is a direct precursor to NAD+, which is critical for cellular energy production, DNA repair, and regulating cellular metabolism. (8) By increasing NAD+ levels, NMN can help activate sirtuins—proteins associated with longevity and cellular repair—and improve mitochondrial function. Higher NAD+ levels are linked to benefits such as enhanced cellular resilience, increased energy, improved cognitive function, and healthier aging. (6)
People who take NMN are typically interested in boosting NAD+ levels specifically to support processes like DNA repair, mitochondrial health, and overall cellular vitality. (6)
Resveratrol, on the other hand, is a polyphenol found in foods like red grapes, blueberries, and peanuts. It is often celebrated for its antioxidant, anti-inflammatory, and cardioprotective properties. (13) Resveratrol is known to help activate sirtuins as well, specifically SIRT1, which is associated with regulating cellular stress and promoting longevity. (11) By activating these pathways, resveratrol may support heart health, protect against oxidative stress, and potentially reduce inflammation. (11)
NMN is primarily associated with enhancing energy production and cellular repair (4), while resveratrol is often favored for its cardiovascular benefits and its ability to combat oxidative stress.
FAQs
What is NMN?
Nicotinamide mononucleotide (NMN) is a naturally occurring molecule created by the body and found in fruits and vegetables (cabbage, tomatoes, broccoli, and avocados). It’s an immediate precursor to NAD+, a coenzyme, and an essential component for many cellular functions, including DNA repair and energy metabolism. (4)
Is NMN safe?
Yes, NMN is typically safe and well-tolerated by the body in daily amounts of 900mg. However, not enough substantial research is available to determine its effects on pregnant and breastfeeding women, children, and people taking certain medicines. In general, NMN potentially has mild side effects, which include nausea, fatigue, indigestion, and headaches. (21)
What is NMN good for?
NMN is good for your body and mind as it increases NAD levels to repair, restore, and re-enable functions at a cellular level. These cellular-level changes may holistically affect the body and improve neurohealth, cardiohealth, cellular health, physical activity, and insulin sensitivity. (21)
Does NMN really work?
Yes, there are studies and personal testimonies that suggest NMN really works. Users typically feel results in two to three weeks, but we’ve seen claims of seeing benefits within a few days. (21)
This makes sense as studies detail that it takes two to three minutes for NMN to be absorbed from the digestive system into the bloodstream, and it fully clears from blood circulation into the body’s tissues within 15 minutes. (25) What comes into question is the intensity of the benefits seen or felt in shorter periods. Typically, results are more noticeable the longer a supplement is taken.
However, people have different experiences with and responses to variable doses of NMN. An individual may not notice, see, or feel any changes due to NMN supplementation.
What is the best form of NMN to take?
The best form of NMN to take is typically oral capsules or sublingual tablets, as these are the most commonly studied and accessible forms with good bioavailability. Some other options include:
- Powder: NMN powder can be mixed into water or other beverages. This form offers flexibility in dosing and can be more cost-effective, but it may be less convenient for some users compared to capsules or tablets.
- Liposomal NMN: Some formulations use liposomal delivery, which encapsulates NMN in fat molecules to enhance absorption. This form may improve bioavailability by protecting NMN from degradation in the digestive system. (16)
What is the best brand of NMN?
The best brand of NMN may vary based on individual preferences and needs, but a few reputable brands are consistently recognized for their quality, purity, and efficacy. Tru Niagen is a well-established brand known for scientific backing. It’s a popular choice for those seeking a trusted name and patented formula in NAD+ support. ProHealth Longevity offers both powder and capsule forms of NMN, with a focus on high-quality, third-party tested ingredients. Nutricost is popular for offering budget-friendly NMN capsules without compromising on quality.
Are NMN products FDA approved?
NMN products are not FDA-approved, as the FDA has not officially sanctioned NMN as a dietary supplement or approved it for any specific medical use. (26) However, NMN is generally marketed and sold as a dietary supplement in the United States, meaning it doesn’t require pre-market approval from the FDA but must comply with regulations governing dietary supplements.
In late 2022, the FDA indicated that NMN might not qualify as a dietary ingredient due to its prior investigation as a new drug. (26) This has created some uncertainty about the future of NMN supplements. As a result, the FDA issued warning letters to some NMN manufacturers, suggesting that NMN could no longer be sold as a dietary supplement. While NMN is not currently banned in the United States, this regulatory scrutiny means there could be restrictions in the future.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases.
Our experts
Dr. Aneesha Dhargalkar
Dr. Aneesha Dhargalkar is a board-certified emergency medicine physician currently practicing in West Chester, PA. She graduated cum laude from John Hopkins University in 2002 and from Jefferson Medical College in 2006. After this, Dr. Dhargalkar attended and completed a three-year residency program in emergency medicine at Temple University Health System. Dr. Dhargalkar is the director of her hospital’s wellness provider program and sits on the executive board of both the Chester County Suicide Prevention Task Force and the Unionville Chadds Ford School District Education Foundation.
Heather Morsellino
Heather Morsellino is a freelance writer and fact-checker with over four years of experience in healthcare. She has worked as a pharmacy technician, emergency room medical scribe, and anesthesia technician in the operating room and will finish her ADN within the following year.
Spencer Kildare, CLC
Fortune Recommends Writer
About Author
Spencer Kildare is a talented and published retail consultant with over ten years of experience in the industry. He uses his expertise and knowledge in product and service writing and has written for media brands such as Reader’s Digest. Spencer earned his certification as a Longevity Coach with the Spencer Institute. In his spare time, Spencer operates media businesses and projects.
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