Cognitive enhancement isn’t just for professionals and students; it’s becoming a priority for anyone looking to improve focus, memory, and mental clarity. As the demand for nootropic supplements grows, more people are turning to products that promise to boost brain function and support cognitive health.
The Alpha Brain product line from Onnit is one of the most well-known in this space, offering a range of supplements designed to help enhance mental performance. Our team of nutrition and health experts reviewed each product in the Alpha Brain lineup, evaluating them based on key criteria such as dose efficacy, potential side effects, price per serving, and overall customer satisfaction.
Read on for our team’s honest and detailed review of the Onnit Alpha Brain supplement line, so you can make an informed decision about which product may be right for you.
Medical disclaimer: This article is intended for educational and informational purposes only. It is not intended as a substitute for medical advice. For health advice, contact a licensed healthcare provider.
Compare Onnit Alpha Brain products
|
|
|
|
|
|
| Onnit Alpha Brain | Onnit Alpha Brain Black Label | Onnit Alpha Brain Pre-Workout | Onnit Alpha Brain Focus Shot | Onnit Alpha Brain Instant | |
| Rating | |||||
| Cost per serving | $1.55 | $6.25 | $3.00 | $3.20 | $2.00 |
| Active ingredients | L-theanine, phosphatidylserine, alpha GPC, huperzine serrata extract, vitamin B6 | Cognizin® Citicoline, huperzia serrata, caffeine anhydrous, L-theanine, phosphatidylserine, Lutemax2020®, mucuna pruriens | Ashwagandha, L-citrulline, alpha-GPC, beta-alanine, caffeine anhydrous | Cognizin® Citicoline, lion’s mane, L-theanine, caffeine, huperzia serrata extract | L-theanine, alpha-GPC, huperzia serrata extract, vitamin B6 |
| Serving | 2 capsules | 4 capsules | 1 scoop | 1 bottle | 1 packet |
Key product features
What you should know
Onnit Alpha Brain is a popular nootropic designed to boost focus and memory. Here are our key takeaways:
- The blend of ingredients in Alpha Brain may help support cognitive function, though the use of proprietary blends makes it difficult to assess their effectiveness.
- At $1.55 per serving, Alpha Brain is relatively expensive compared to other nootropics.
- This supplement is best for individuals looking to enhance mental clarity and focus, particularly in high-pressure situations or tasks requiring sustained cognitive effort.
Why we like Onnit Alpha Brain
Onnit Alpha Brain is formulated to enhance cognitive functions like focus and memory, making it a popular choice among nootropic enthusiasts. The formula includes a combination of vitamins, herbal extracts, and proprietary blends aimed at supporting acetylcholine production and promoting alpha brain waves, which are linked to a relaxed yet alert state of mind. (1, 2)
The supplement contains 10 milligrams of vitamin B6, which plays a crucial role in neurotransmitter synthesis, including serotonin and dopamine, both of which are involved in mood regulation and cognitive function. While this is a beneficial addition, vitamin B6 is commonly found in many foods and multivitamins, so its inclusion may not stand out as much. Further, while B6 and other B vitamins are important, data don’t show that adding more to the body is helpful without a deficiency or insufficiency. (3)
A key component of Alpha Brain is the Onnit Flow Blend, which totals 650 milligrams (mg) and includes L-tyrosine, L-theanine, oat straw extract, and phosphatidylserine. The use of a proprietary blend is worth noting because it conceals the specific amounts of each ingredient. This can be problematic since it’s difficult to determine if the dosages match those used in clinical studies. For instance, L-theanine is typically effective at doses of 100-200 mg, but without knowing the exact amount in Alpha Brain, it’s unclear how much benefit users might receive. (4)
“Proprietary blends are an unfortunate inclusion in my dietary supplements because you have no idea what amount of each ingredient is in the product, explains Chris Mohr, PhD, RD. “While the ingredients themselves may have merit, without knowing the amounts to match the research around each of them, it’s impossible to determine the overall utility of any dietary supplement.”
Another blend in the formula is the Onnit Focus Blend, which includes alpha-GPC, bacopa extract, and huperzine A. Alpha-GPC is known for its potential to support cognitive function by increasing acetylcholine levels, and bacopa extract has been studied for its ability to support memory and learning. (5, 6) Of note, the latter study on bacopa was specific to individuals with neurodegenerative disease and while intriguing, should not be extrapolated to otherwise healthy individuals. Further, as with the Flow Blend mentioned earlier, the proprietary nature of this blend makes it difficult to assess the efficacy of each ingredient.
The formula also includes 350 mg of cat’s claw bark extract, which is claimed to have neuroprotective properties. While some research supports its use, the evidence is not conclusive and much of the data are in Alzheimer’s patients vs. younger, healthy individuals. (7)
One concern with Alpha Brain is the lack of specific information about third-party testing. Although Onnit claims that many of its products are third-party tested for purity and banned substances, there’s no explicit mention of this for Alpha Brain, which may be a consideration for potential users.
“One interesting aspect of Alpha Brain is that it has a couple of research studies measuring its outcomes specifically,” notes Mohr. “In the publications from the study, the researchers found that over 6 weeks, the young (18-35 year old subjects) taking Alpha Brain vs. placebo had improved their recent verbal memory,” he explained. (8, 9)
A 45-day supply costs $69.90. This breaks down to approximately $1.55 per two-capsule serving, placing it in the mid-to-high range compared to other nootropic supplements on the market. While this may be on the pricier side, the unique blend of ingredients and the reputation of the Onnit brand could justify the investment for those seeking cognitive enhancement.
What customers are saying
Amazon customers have given Onnit Alpha Brain a 3.9 out of 5 average rating, based on over 1,600 reviews. Many users praise the supplement for its effectiveness in enhancing focus and mental clarity, though some have experienced mixed results.
“After using it only a few days it made a great difference already.”
Rene, Amazon
Another Amazon customer, Thomas F., highlighted the cognitive benefits he’s noticed, especially while going through nursing school. “On days that I use this, my thought process just keeps flowing. I’m so productive that I’ve finished entire research papers in a single sitting. Memorization and recall of anatomy were wonderfully surprising to me as if I had been studying all week versus a single night of study.”
However, not all feedback is positive. Some customers have reported side effects or felt that the product didn’t live up to their expectations. For instance, verified Amazon customer Penny noted, “Honestly it didn’t make any difference in my life and it didn’t give me more energy.”
Specs
| Serving size | 2 capsules |
| Key ingredients | L-theanine, phosphatidylserine, alpha-GPC, huperzine serrata extract, vitamin B6 |
| Calories | N/A |
| Servings per container | 45 |
| Cost per serving | $1.55 |
| Caffeine | None |
Key product features
What you should know
Onnit Alpha Brain Black Label is a high-end nootropic formulated for those who need an extra mental boost. The formula is gluten-free, dairy-free, and soy-free.
- The formula features powerful ingredients like Mucuna pruriens (1,000 mg) and lion’s mane (500 mg), specifically chosen for their ability to help enhance cognitive function.
- Priced at $124.95 for a 20-day supply, it’s a considerable investment, but the high potency and potential effectiveness may justify the cost for dedicated users.
- This supplement is best for those needing a bigger mental boost than what they can achieve with the regular Alpha Brain formula, especially during high-pressure situations or demanding tasks.
Why we like Onnit Alpha Brain Black Label
Onnit Alpha Brain Black Label is a premium nootropic supplement designed to provide an extra boost of focus and productivity when you need it most. With a formulation that includes a blend of herbal extracts, amino acids, and other cognitive-enhancing ingredients, Alpha Brain Black Label stands out as a potent option for those looking to sharpen their mental edge.
The formula contains 1,000 mg of velvet bean (Mucuna pruriens) extract, standardized to 15% L-Dopa. L-Dopa is a precursor to dopamine, a neurotransmitter that plays a crucial role in motivation, focus, and mood regulation. Limited human research exists on Mucuna pruriens, and while clinical trials suggest it may help alleviate Parkinson’s disease symptoms, this doesn’t directly translate to enhancing clarity and productivity in healthy individuals. People taking L-Dopa or diabetes medications should avoid using this supplement. (10, 11)
Lion’s mane, included at 500 mg, is another key ingredient known for its potential neuroprotective benefits. It has been studied for its role in supporting brain health and promoting nerve growth factor (NGF) production, which is essential for the maintenance and growth of neurons. However, most studies utilize dosages of 1,000-3,000 mg, meaning this formula is clinically underdosed. (12)
Cognizin® citicoline is a compound that supports cognitive function by increasing the levels of phosphatidylcholine in the brain, a component critical for healthy brain cell membranes. Research has shown that citicoline may improve memory and mental energy, making it a valuable addition to a nootropic formula. Phosphatidylserine has been associated with improved cognitive function, particularly in older adults, and may help reduce cognitive decline and other studies have found positive effects in young, healthy adults (13) It should be noted that most data dose between 500-2000 mg of Cognizin, whereas Alpha Brain Black Label, has just 250 mg per serving. (13)
The formula also includes 100 mg of L-theanine, an amino acid commonly found in tea leaves, which is known for promoting relaxation without drowsiness. When combined with caffeine, which is included in this supplement at a 25 mg dose, L-theanine can enhance focus and attention while mitigating the jittery effects that caffeine alone might produce. (4, 14)
Huperzia serrata extract, standardized to provide 200 micrograms (mcg) of huperzine A, helps prevent the breakdown of acetylcholine, a neurotransmitter involved in learning and memory. This may help improve cognitive function, though more studies in healthy individuals are needed. (15)
This supplement also includes 20 mg of lutein and 4 mg of zeaxanthin isomers from Lutemax 2020® Marigold. These ingredients may protect our eyes from blue light and oxidative stress, which is a thoughtful addition for those who spend a lot of time in front of screens. (16, 17)
Onnit Alpha Brain Black Label is marketed as a stronger alternative to the original Alpha Brain and is recommended for use when you need an extra mental edge. The product is dairy-free, gluten-free, and soy-free, catering to those with dietary restrictions.
At $124.95 for a 20-day supply, Alpha Brain Black Label is a significant investment. Onnit offers a subscription service that reduces the cost by 25% on the first order and 15% on subsequent orders, which may make it more accessible for regular users.
While the formulation is robust, it’s important to note that the high price and the specific use case of “when you need it most” may limit its appeal to those seeking an everyday cognitive enhancer. Further, even at the premium price, some ingredients still don’t meet the research-supported outcomes desired, which is disappointing when paying a premium price for a premium-marketed product. Additionally, the lack of specific mention of third-party testing for this product might concern some users who prioritize transparency in their supplement choices.
What customers are saying
On Amazon, Onnit Alpha Brain Black Label has earned a 3.9- out of 5-star rating from 745 global reviews. Many users appreciate the stronger effects compared to the standard Alpha Brain capsules, particularly when it comes to focus and productivity.
“I’ve used the regular formula for some time. I’m an engineer and need to focus, and this product gave me a boost right away. I’m pleasantly surprised at the result.”
Username “Mr D NV,” Amazon
Another Amazon customer, Tyler Fox, echoes this sentiment: “I absolutely love all of the Alpha Brain products. This Black Label takes it to a whole new level. This product gives everything it says and more.”
The biggest complaint seems to be the price. Even many of the positive reviews mention the cost. For example, Amazon customer Shane O notes that this supplement has prime ingredients, but “the price is insane for 20 days’ worth.”
“Shockingly, this seemed far less effective than the Onnit single-serve packets you put in water,” writes Amazon customer Victor Ricci.
Specs
| Serving size | 4 capsules |
| Key ingredients | Cognizin® Citicoline, huperzia serrata, caffeine anhydrous, L-theanine, phosphatidylserine, Lutemax2020®, mucuna pruriens |
| Calories | N/A |
| Servings per container | 20 |
| Cost per serving | $6.25 |
| Caffeine | 25 mg |
Key product features
What you should know
Onnit Alpha Brain Pre-Workout is designed to help enhance both mental focus and physical performance during workouts, combining nootropics with traditional pre-workout ingredients.
- Our product testers rated the taste 4 out of 5 stars, with Tiger’s Blood being their preferred flavor. They gave full marks for solubility.
- At just under $3.00 per serving, Alpha Brain Pre-Workout is on the pricier side. The blend of ingredients might justify the cost for those seeking a comprehensive workout supplement.
- With 200 mg of caffeine, Alpha Brain Pre-Workout is best for individuals working out earlier in the day.
Why we like Onnit Alpha Brain Pre-Workout
Onnit Alpha Brain Pre-Workout is designed to elevate your exercise performance by helping to enhance focus, energy, and endurance. The formula includes 225 mg of ashwagandha, known for reducing stress and improving mood, though this dose is slightly below the typical 300-600 milligram range recommended in studies. (18)
Caffeine anhydrous, at 200 mg per serving, is a staple in many top pre-workouts due to its ability to enhance focus, energy, and alertness. (19) This amount is equivalent to about two cups of coffee, providing a moderate energy boost without going overboard. The inclusion of 125 mg of alpha-GPC further supports cognitive function, potentially enhancing mental clarity and focus during workouts, and in one study, it supported increased motivation. It should be noted that the dose used in this study (200 or 400 mg) is more than the 125 mg contained in this product. (5)
Beta-alanine is another popular pre-workout ingredient known for its ability to buffer lactic acid in muscles, which can help delay fatigue and enhance endurance during high-intensity exercise. (20) L-citrulline is renowned for its role in boosting nitric oxide production. Increased nitric oxide levels can enhance blood flow, improving nutrient and oxygen delivery to muscles, which may result in better performance and reduced muscle soreness. (21) However, the 2.4 gram doses of each of these ingredients are below the clinical ranges of 4-6 grams of beta alanine and 6-8 grams of L-citrulline,respectively, which might limit their effectiveness. (20, 21)
Theobromine, dosed at 100 mg, is a mild stimulant found in chocolate that can provide a smoother, longer-lasting energy boost compared to caffeine, while also offering potential cardiovascular benefits. (22)
Dynamine, a compound similar to caffeine, is included at a dose of 50 milligrams to offer quick, sustained energy without the jitters or crash often associated with high-caffeine pre-workouts. 23)
The inclusion of African oil palm fruit extract (PFBc) may provide antioxidant benefits and support cognitive function by reducing oxidative stress. At least one study suggests it has potential (24)
Onnit Alpha Brain Pre-Workout is gluten-free, sugar-free, and contains no synthetic colors or dyes, catering to those with dietary restrictions or preferences for cleaner supplements. It’s available in two flavors, yuzu peach and tiger’s blood, giving users some variety in taste.
Each container of Onnit Alpha Brain Pre-Workout costs $59.99 for 20 servings, breaking down to approximately $3.00 per serving. This is on the higher end of the price spectrum for pre-workouts, with many competitors ranging between $1.00 to $2.00 per serving. However, Onnit offers a subscription plan that reduces the cost by 25% on the first order and 15% on subsequent orders.
What customers are saying
Onnit Alpha Brain Pre-Workout has an average rating of 3.2 out of 5 stars based on 46 ratings on Amazon. This seems to be for the yuzu peach flavor, specifically. The tiger’s blood flavor is currently not listed on Amazon.
Many customers note that the yuzu peach flavor is not enjoyable.
“This is literally the only Onnit product I’ve tried that I didn’t like,” writes Amazon customer Briana. “The Yuzu Peach flavor was atrocious.”
Specs
| Serving size | 1 scoop (9.6–10.4 g) |
| Key ingredients | Varies by product; the Peach flavor includes Ashwagandha, L-citrulline, alpha-GPC, beta-alanine, caffeine anhydrous, theobromine, Dynamine, African oil palm fruit extract (PFBc) |
| Calories | 0–5 |
| Servings per container | 20 |
| Cost per serving | $3.00 |
| Caffeine | 200 mg |
Key product features
What you should know
Onnit Alpha Brain Focus Shot is a portable and potentially effective solution for enhancing focus and mental clarity—designed for those needing a fast-acting cognitive boost on the go.
- The high dosage of vitamin B12 (500 mcg) is much higher than the recommended daily allowance but is generally safe due to its water-soluble nature. (23)
- At around $3.20 per shot, it’s more expensive than many other nootropic options, but the convenience and formulation may justify the price.
- Alpha Brain Focus Shot is ideal for individuals needing an immediate mental boost, especially during busy or demanding situations where convenience is key.
Why we like Onnit Alpha Brain Focus Shot
Onnit Alpha Brain Focus Shot is designed to provide a quick and convenient boost in focus and mental clarity, making it a good go-to option for those needing an immediate cognitive lift. Each shot (2.5 fluid ounces) is packed with a blend of nootropic ingredients aimed at enhancing mental performance, all while being gluten-free and sugar-free. Available in peach or tropical flavors, it offers both taste and functionality in a small package.
The formula contains 10 calories and 30 mg of sodium, making it a low-calorie, low-sodium option that won’t significantly impact your daily intake. It includes 5 mg of vitamin B6, which is essential for neurotransmitter production, supporting brain function and mood regulation. (3)
One of the standout components is the 500 mcg of vitamin B12, a dosage that is extremely high compared to the recommended dietary allowance of 2.4 mcg. While such a high dose might raise concerns, it’s worth noting that vitamin B12 is water-soluble, meaning the body excretes any excess through urine. Therefore, this high dosage is likely not dangerous for most individuals, although those with certain health conditions should consult a healthcare provider. (25) And, further, while likely not harmful, it’s also less likely to have any benefit either.
The shot also contains 1000 mg of N-acetyl L-tyrosine, an amino acid that supports the production of dopamine, a neurotransmitter involved in focus, motivation, and mood. This ingredient may be particularly beneficial in stress-filled situations where cognitive performance might be impaired, though most data using this ingredient suggest double the dose of that which is included in this supplement (26)
Organic ashwagandha extract, supplied here at 300 mg, is known for its adaptogenic properties that help manage stress and reduce anxiety. This can contribute to a more balanced mental state, allowing for better focus and productivity. And while the dose included, 300 mg, is on the lower end of where most data suggest a potential benefit, 300 mg has been effective in some. (18)
There’s also 250 mg of Cognizin citicoline, a compound that supports brain energy and cognitive function by increasing phosphatidylcholine levels in the brain. This ingredient is well-regarded in the nootropic community for its potential to enhance memory and mental clarity, but at least double the dose (and in some studies up to 2000 mg compared to the 250 mg in this product. (13)
The formula also features 250 mg of lion’s mane, a mushroom extract known for its neuroprotective properties. Lion’s mane may support brain health by promoting nerve growth factor (NGF), which is vital for the maintenance and growth of neurons. Added benefits and potential for this ingredient are at around 3 grams daily, which is a significantly higher dose than is included in this supplement. (12)
L-theanine, dosed at 100 mg, is an amino acid commonly found in tea that promotes relaxation without causing drowsiness. It works synergistically with caffeine, which is included in the form of 50 mg of natural caffeine sourced from green tea leaf extract. This combination can enhance focus and attention while reducing the jitteriness that caffeine alone might cause. (4, 14)
Onnit Alpha Brain Focus Shot is priced at $23.99 for a 6-count of bottles, which breaks down to about $4.00 per shot. A 24-count is available for $76.77, reducing the cost per shot to approximately $3.20. This price range is relatively standard for nootropic shots, although some competitors may offer lower prices depending on the ingredient quality and formulation.
What customers are saying
On Amazon, the Alpha Brain Focus Shot in the tropical flavor has an average rating of 3.8 out of 5 stars, while the peach flavor has an average rating of 4.0 out of 5 stars. Most customers are pleased with the quality and effectiveness of the supplement.
“This is a life saver. I haven’t felt this good in years. This is not like a stimulant, it doesn’t make you feel jittery and it lasts all day.”
Brandi, Amazon
However, opinions are mixed when it comes to taste and value. Amazon customer Belen notes, “It tastes gross, but worth it.”
“The flavors of these energy shots are never great, but the effect is worth it,” writes Sarah Dilley.
Specs
| Serving size | 1 bottle (2.5 fluid ounces) |
| Key ingredients | Cognizin® citicoline, lion’s mane, L-theanine, caffeine, huperzia serrata extract, N-acetyl L-tyrosine, ashwagandha, vitamin B12, vitamin B6 |
| Calories | 10 |
| Servings per container | 24 |
| Cost per serving | $3.20 |
| Caffeine | 50 mg |
Key product features
What you should know
Onnit Alpha Brain Instant offers a convenient, mixable solution to support cognitive enhancement, featuring a blend of nootropics designed to boost focus and memory.
- The stick pack format makes Alpha Brain Instant convenient for on-the-go use, with a slightly different ingredient blend compared to the original Alpha Brain formula.
- Priced at about $2.00 per serving, it’s competitively priced for a premium nootropic, especially considering the convenience it offers.
- Alpha Brain Instant is ideal for those who prefer a drinkable supplement compared to the Alpha Brain capsules.
Why we like Onnit Alpha Brain Instant
Onnit Alpha Brain Instant is a nootropic supplement designed to provide cognitive support in a convenient, easy-to-use stick pack. Whether you’re at home or on the go, Alpha Brain Instant allows you to mix your nootropic drink quickly and efficiently. The product is caffeine-free and gluten-free, making it suitable for a variety of dietary needs. It’s available in five flavors—pineapple punch, peach, meyer lemon, blackberry lemonade, and ruby grapefruit—offering a refreshing option for everyone.
Each 10-calorie serving contains 10 mg of vitamin B6, which supports neurotransmitter synthesis, essential for cognitive function and mood regulation. (3)
The formula includes 1.15 g of the Onnit Flow Blend, a proprietary mix of L-tyrosine, L-theanine, oat straw extract, and phosphatidylserine. These ingredients are known for their roles in enhancing focus, relaxation, and mental clarity. The inclusion of L-tyrosine, an amino acid, supports dopamine production, which can help improve focus, especially under stress. (26) L-theanine, commonly found in tea, promotes relaxation without drowsiness, while oat straw extract and phosphatidylserine support brain health and cognitive function. (4, 27 28)
The supplement also includes 350 mg of cat’s claw, an herbal extract that may offer neuroprotective benefits, though more research is needed to fully confirm its effects, since most of the data are in those with pre-existing memory concerns, such as Alzheimer’s. (7)
The Onnit Focus Blend, consisting of alpha-GPC, bacopa extract, and huperzine A, is designed to support memory, learning, and mental clarity. Alpha-GPC is known for its potential to increase acetylcholine levels in the brain, a neurotransmitter critical for learning and memory. (5) Bacopa extract, an adaptogen, has been shown in some studies to support cognitive function, while huperzine A works by inhibiting the breakdown of acetylcholine, further enhancing cognitive performance. (6, 15)
To note, the supplement contains three proprietary blends, which makes it impossible to assess the effectiveness of the ingredients and the supplement overall. The caffeine-free blend may also provide cognitive support without the jitters for users more sensitive to caffeine.
Alpha Brain Instant differs from the original Alpha Brain and Alpha Brain Focus Shot primarily in its form. While Alpha Brain comes in capsule form and Alpha Brain Focus Shot is a liquid shot, Alpha Brain Instant is a powder that you can mix into water, making it a convenient option for those who prefer a drinkable supplement.
Additionally, the ingredients in Alpha Brain Instant are slightly adjusted compared to its counterparts. For instance, this formula contains 1,150 mg of the Flow Blend, while the original Alpha Brain contains 650 mg. Again, however, “more” when in a proprietary blend is meaningless.
“Proprietary formulas do a disservice to the supplement industry as you can never determine the quantities within a product and therefore can never compare a product’s ingredients to the research itself,” adds Mohr.
Each 30-day supply of Alpha Brain Instant costs $59.95, which breaks down to about $2.00 per serving. This price is competitive compared to other premium nootropic supplements on the market, especially given the convenience of the stick pack format. Onnit also offers a subscription option that saves 25% on the first order and 15% on future orders, making it a more affordable option for regular use.
What customers are saying
On Amazon, Onnit Alpha Brain Instant has an average rating of 4.3 out of 5 stars across all five flavors. The pineapple punch flavor is the only one with a 4.2 rating. Most customers are pleased with the effectiveness and taste.
“It works really well. Clears the brain fog and gives me that boost I need for busy days at work.”
Tim B., Amazon
The pineapple punch flavor seems to have the most negative feedback in terms of taste. Some customers report side effects like stomach discomfort and headaches. Others have mixed opinions on the results.
“I’m a big fan of this product and drink a packet instead of reaching for a cup of coffee or an energy drink,” writes Amazon customer Kim. “The pineapple flavor is pretty gross in my opinion though, so I don’t recommend that flavor. The original flavor is great though.”
Another Amazon customer, Megan Casler, enjoys the taste of Alpha Brain Instant, but notes, “I have taken it a few times so far and didn’t notice any change in my ability to focus or general awareness. No negative effects, but also no positive effects either.”
Specs
| Serving size | 1 packet (3.4–4.6 grams) |
| Key ingredients | L-theanine, alpha-GPC, huperzia serrata extract, vitamin B6, L-tyrosine, oat straw, phosphatidylserine, bacopa, cat’s claw |
| Calories | 10 |
| Servings per container | 30 |
| Cost per serving | $2.00 |
| Caffeine | None |
How we test supplements
We’re dedicated to providing supplement reviews that you can trust. We thoroughly test each product we recommend and offer genuine, impartial feedback. Learn more about our supplement testing methodology, which covers everything from ingredient purity to effectiveness and taste. Here’s how we evaluated Alpha Brain supplements in this review.
Efficacy—40%
Consumers turn to nootropic supplements to achieve specific cognitive benefits, so we carefully assess whether Alpha Brain delivers on its promises. Efficacy includes not only the product’s ability to meet its claims but also the scientific evidence supporting those claims.
We consider:
- Clinical evidence
- Calories per serving
- Dose efficacy
- Synergistic effects
- Proprietary blends
Safety and side effects—35%
Safety is a top priority when evaluating supplements, as potential health risks, side effects, and the overall safety profile of the product are crucial. Our testing ensures that Alpha Brain is safe for consumption.
We assess:
- Reported side effects
- Third-party testing
- Manufacturer accreditation
- Artificial sweeteners
Value—20%
Value isn’t just about price—it’s also about the quality and effectiveness of the product relative to its cost. We analyze the cost of Alpha Brain to determine whether it offers a good return on investment.
Our factors in this rating include:
- Price per serving
- Subscriptions
Customer experience—5%
A positive customer experience is key to satisfaction, loyalty, and repeat purchases. We consider customer experience in our review because it plays a significant role in the purchasing decision.
We look at:
- Ease of purchase
- Shipping and returns
- Customer support
How does Alpha Brain work?
The Alpha Brain line of supplements from Onnit is designed to enhance cognitive function by targeting various aspects of brain health. Whether in capsule form, instant drink mixes, or convenient shots, Alpha Brain products combine nootropic ingredients to support neurotransmitter production, promote alpha brain wave activity, and improve mental clarity. Key ingredients like L-tyrosine, L-theanine, and alpha-GPC are included across the product line to help boost focus, memory, and cognitive flexibility. Additionally, each product is formulated to address specific needs—whether you’re seeking daily cognitive support, a pre-workout boost, or a quick mental pick-me-up.
How much does Alpha Brain cost?
The cost of Alpha Brain supplements varies depending on the specific product and format. The standard Alpha Brain capsules are priced at $69.90 for a 45-day supply, with other products like Alpha Brain Instant and Alpha Brain Focus Shot offering different price points.
- Onnit Alpha Brain: $69.90 for 45 servings
- Onnit Alpha Brain Black Label: $124.95 for 20 servings
- Onnit Alpha Brain Pre-Workout: $59.99 for 20 servings
- Onnit Alpha Brain Focus Shot: $76.77 for 24 servings
- Onnit Alpha Brain Instant: $59.95 for 30 servings
Onnit offers subscription plans across the line, allowing customers to save 35% on their first order and 15% on future orders, making the products more affordable for regular use. The pricing is in the mid-to-high range for nootropic supplements, reflecting the quality and reputation of the Onnit brand.
Alpha Brain side effects
While the Alpha Brain line is generally well-tolerated, users may experience some side effects depending on their sensitivity to the ingredients. Common side effects across the product range include headaches, nausea, and digestive discomfort, which can occur due to the potency of the ingredients or individual reactions.
Specific ingredients like huperzine A, found in several Alpha Brain products, may lead to vivid dreams or sleep disturbances if taken late in the day. (29) Ashwagandha may cause an upset stomach, nausea, diarrhea, or drowsiness when taken in high doses. (30) One large cohort study in South Korea found that individuals who supplemented with alpha-GPC had a higher 10-year risk of stroke, however more research is needed. (31)
Additionally, the inclusion of stimulants in products like Alpha Brain Pre-Workout could cause jitters or increased heart rate in caffeine-sensitive individuals. Beta-alanine often causes a tingling sensation (paresthesia) in the skin, which is harmless but can be uncomfortable for some users.
As with any supplement, it’s important to consult with a healthcare provider before starting any product from the Alpha Brain line, especially if you have underlying health conditions or are taking medications.
Who should consider Alpha Brain?
The Alpha Brain line of supplements is ideal for individuals looking to enhance cognitive performance in various aspects of their lives. Professionals, students, and athletes who require sustained focus, memory enhancement, and mental clarity may benefit from these products.
Each supplement within the line caters to specific needs: the standard Alpha Brain capsules for daily cognitive support, Alpha Brain Instant for those who prefer a mixable drink option, Alpha Brain Pre-Workout for those needing both mental and physical energy, Alpha Brain Black Label for those needing a more potent cognitive enhancement during critical tasks, and Alpha Brain Focus Shot for a quick, portable boost.
However, these products may not be suitable for individuals sensitive to certain nootropic ingredients or those who prefer stimulant-free options, as some products in the line contain caffeine and other stimulants.
We’ve featured Alpha Brain products in:
- Best brain health supplements
- Best pre-workout supplements for women
- Best pre-workout supplements
- Best nootropics
- Strongest pre-workout supplements
Onnit Alpha Brain vs.
|
|
|
|
|
|
|
| Onnit Alpha Brain | Legion Ascend | Lifeforce Peak Rise | Sports Research L-Theanine + Caffeine | Promix Flow State | |
| Rating | |||||
| Cost per serving | $1.55 | $1.67 | $4.00 | $0.37 | $1.60 |
| Active ingredients | L-theanine, phosphatidylserine, alpha GPC, huperzine serrata extract, vitamin B6 | Avena Sativa, agmatine sulfate, bacopa monnieri, alpha-GPC, uridine monophosphate | Dynamine®, TeaCrine®, caffeine, Acetyl-L-carnitine HCl, Alpinia galanga, Panax ginseng, choline, sage, IQ200 | MCT oil, L-theanine, caffeine | Vitamin C, folate, vitamin B12, L-tyrosine, citicoline, L-theanine, theacrine, mucuna pruriens |
| Serving | 2 capsules | 4 capsules | 3 capsules | 1 softgel | 1 scoop |
FAQs
Is Alpha Brain as good as Adderall?
Alpha Brain and Adderall serve different purposes and are not directly comparable. Adderall is a prescription medication used to treat ADHD and narcolepsy, while Alpha Brain is a dietary supplement designed to enhance focus, memory, and cognitive performance in healthy individuals.
Alpha Brain may help improve mental clarity and focus, but it does not have the same potency or specific effects as Adderall. Always consult a healthcare provider before considering alternatives to prescription medications and never stop taking an existing medication without consulting a professional
Is Alpha Brain FDA-approved?
No, Alpha Brain products are not FDA-approved. However, Onnit, the maker of Alpha Brain, manufactures all of its products in NSF-certified Good Manufacturing Practices (GMP) facilities to ensure product quality and safety. The products are not third-party certified, however.
Can you drink coffee if you take Alpha Brain?
Yes, you can generally drink coffee if you take Alpha Brain supplements, but it depends on which product you take and your sensitivity to caffeine. Some Alpha Brain products, like Alpha Brain Pre-Workout, already contain caffeine, so additional coffee would increase your caffeine intake and potentially lead to jitters or restlessness. If you are sensitive to caffeine, consider starting with a lower dose of Alpha Brain or spacing out your coffee consumption to monitor how your body responds.
These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases.
Our experts
Victoria Burgess, Ph.D., CSCS, CISSN
Victoria Burgess earned her Ph.D. in Health and Human Performance from Concordia University Chicago and holds her NSCA CSCS and Certified Sports Nutritionist (CISSN). She is an adjunct professor in the Human Performance and Nutrition department at Concordia University Chicago & Parker University, where she teaches undergraduate, graduate, and doctoral level courses.
Chris Mohr, Ph.D., RD
Dr. Christopher Mohr is an internationally recognized subject matter expert, speaker, and performance coach. He works closely with some of the largest corporations in the world including Deloitte, Delta Airlines, Johnson & Johnson, and more to help busy executives develop the energy to thrive personally and professionally. Chris was a member of the Men’s Health Magazine advisory board for 10 years, co-authored a NY Times Bestseller with LL Cool J, called LL Cool J’s Platinum Workout, and worked as the sports nutritionist for the Cincinnati Bengals and select WWE wrestlers.
Jessica Coulon
Jessica Coulon is a contributing editor and writer for Fortune Recommends™ who specializes in fitness, health, nutrition, and science content. Previously, she was an editor for Popular Mechanics and Bicycling, where she covered pro cycling news, wrote how-to guides, and tested all the latest and greatest bike gear. She was also a regular shoe tester and contributor for Runner’s World. You can often find her skiing or riding her mountain bike, and racing with the F1RE female enduro team.
Joana Neziri, M.S., NASM CPT
Joana is a writer, editor, and content strategist focusing on nutrition, fitness, and all things health. After earning a master’s degree in business from the University of North Florida, she began a career in research and digital marketing.
Kelly Uhler
Kelly has a multifaceted background in elder care, health care, and copywriting. She has worked for organizations such as A Place For Mom and Homecare.com, which gave her the opportunity to work closely with families, providing reliable information to help them make informed decisions about their loved one’s health, safety, and quality of life.
Melissa Boufounos, CHN
Fortune Recommends Nutrition Writer